探讨改良振幅整合脑电图（aEEG）评分对高危足月低体质量新生儿脑损伤的评估效果。

回顾性分析邢台市第三医院新生儿科自2017年9月至2019年4月出生的167例高危足月低体质量新生儿的临床资料，依据新生儿是否存在脑损伤[新生儿神经行为评估（NBNA）≤35分]分为脑损伤组和无脑损伤组。分别采用常规aEEG评分标准和改良aEEG评分标准依次对2组新生儿出生12 h内的脑电图进行评分，比较2组新生儿的常规aEEG评分和改良aEEG评分结果，并比较2种评分对高危足月低体质量新生儿脑损伤的诊断结果。

167例高危足月低体质量新生儿中，无脑损伤组83例，脑损伤组84例，其中自然分娩转剖宫产脑损伤发生率高于自然分娩、剖宫产，差异有统计学意义（P<0.05）；脑损伤组的常规aEEG评分和改良aEEG评分均低于无脑损伤组，差异有统计学意义（P<0.05）；改良aEEG评分与常规aEEG评分对高危足月低体质量新生儿脑损伤的评估结果比较，差异均有统计学意义（P<0.05）；改良aEEG评分和常规aEEG评分对高危足月低体质量新生儿脑损伤评估的最佳截断点分别为9分和8分，改良aEEG评分评估脑损伤的受试者工作特征曲线下面积高于常规aEEG评分，差异有统计学意义（P<0.05）。

常规aEEG评分和改良aEEG评分均可用于高危足月低体质量新生儿脑损伤评估，后者效果更好。

To explore the evaluation effect of modified amplitude-integrated electroencephalography (aEEG) scores on brain injury of high-risk full-term low body weight newborns.

The clinical data of 167 high-risk full-term low body weight newborns who were born in Neonatal Department of Xingtai Third Hospital from September 2017 to April 2019 were retrospective analyzed. They were divided into brain injury group and non brain injury group according to the brain injury occurence or not [neonatal behavioral neurological assessment (NBNA) ≤35 scores]. The routine aEEG scoring standard and the modified aEEG scoring standard were used to evaluate the the two groups of newborns' EEG within 12 h after birth, and the results of the routine aEEG scoring and the modified aEEG scoring of the two groups were compared and the diagnostic results of the two scores for the brain injury of high-risk full-term low body weight newborn were compared.

Among 167 high-risk full-term low body weight newborns, there were 83 cases in the non brain injury group and 84 cases in the brain injury group. The incidences of brain injury in spontaneous delivery and cesarean section were higher than that in spontaneous delivery and cesarean section, with a statistically significant difference (P<0.05); The scores of routine aEEG and modified aEEG in brain injury group were lower than those in non brain injury group, with a statistically significant difference (P<0.05); There were significant differences in modified aEEG score and conventional aEEG score on the evaluation of brain injury in high-risk full-term low body weight newborns (P<0.05); the optimum cut-off points of the modified aEEG scores and the routine aEEG scores were 9 and 8. The area under receiver operating characteristic curve of modified aEEG score was larger than that of conventional aEEG score, and the difference was statistically significant (P<0.05).

Both the conventional aEEG scores and the modified aEEG scores can be used to evaluate the brain injury of high-risk full-term low body weight newborns, with the latter showing better results.