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中华神经创伤外科电子杂志 ›› 2018, Vol. 04 ›› Issue (01) : 16 -19. doi: 10.3877/cma.j.issn.2095-9141.2018.01.005

所属专题: 文献

临床研究

创伤性脑损伤术后并发脑积水的临床经验总结
胡世颉1, 李兵1, 费舟1,()   
  1. 1. 710032 西安,空军军医大学西京医院神经外科
  • 收稿日期:2017-11-22 出版日期:2018-02-15
  • 通信作者: 费舟
  • 基金资助:
    国家自然科学基金(81101710); 陕西省社会发展科技攻关项目(2015SF030); 陕西省国际科技合作与交流计划项目(2016KW-011)

Clinical experience on hydrocephalus after surgery of traumatic brain injury

Shijie Hu1, Bing Li1, Zhou Fei1,()   

  1. 1. Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China
  • Received:2017-11-22 Published:2018-02-15
  • Corresponding author: Zhou Fei
  • About author:
    Corresponding author: Fei Zhou, Email:
引用本文:

胡世颉, 李兵, 费舟. 创伤性脑损伤术后并发脑积水的临床经验总结[J/OL]. 中华神经创伤外科电子杂志, 2018, 04(01): 16-19.

Shijie Hu, Bing Li, Zhou Fei. Clinical experience on hydrocephalus after surgery of traumatic brain injury[J/OL]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2018, 04(01): 16-19.

目的

分析总结创伤性脑损伤(TBI)患者术后并发脑积水的高危因素和治疗体会,为降低TBI术后并发脑积水的发生率以及改善治疗效果提供理论依据。

方法

选取空军军医大学西京医院神经外科重症监护室自2014年1月至2016年12月收治的TBI行标准去骨瓣减压术治疗的126例患者作为研究对象,对全部患者进行至少6个月随访,发生脑积水患者纳入脑积水组,未发生脑积水患者纳入对照组,回顾性分析术后脑积水发生率,比较分析TBI术后患者脑积水发生相关的高危因素,并观察脑室-腹腔分流术(VPS)对TBI并发脑积水患者的治疗效果。

结果

126例患者中23例发生脑积水,并发脑积水时间为伤后1~10周。与对照组相比,脑积水组患者术前GCS评分较低(t=8.235,P<0.05),急性生理学与慢性健康评分系统Ⅱ评分较低(t=10.573,P<0.05),差异具有统计学意义。2组在年龄、昏迷时间、血肿部位(硬膜下、脑内)、蛛网膜下腔出血、脑室出血、中线偏移≥10 mm情况有着明显的不同,差异有统计学意义(P<0.05)。脑积水组患者行VPS治疗,28 d内恢复清醒状态,体温正常,无语言障碍。

结论

临床应为TBI患者术前进行术后并发脑积水高危因素的评估,预防脑积水的发生;若已发生,则可通过使用VPS来缓解患者的病情。

Objective

To analyze and summarize the high risk factors of hydrocephalus after surgery of traumatic brain injury (TBI) and therapeutic experiences, and to provide theoretical basis for the prevention of postoperative hydrocephalus.

Methods

To enroll 126 cases of TBI patients with standard decompressive craniectomy and follow up at least with 6 months about the complication rate of hydrocephalus. The related clinical characteristics were compared and the therapeutic results were observed after ventriculo-peritoneal shunt (VPS).

Results

Age, time of coma, lower GCS and high APACHEⅡscore when admission, location of hematoma, subarachnoid hemorrhage, intraventricular hemorrhage, lumbar puncture, intra-operative dura suture and midline shift more than 10 mm were the high risk factors of hydrocephalus after standard decompressive craniectomy of TBI patients. There were significant differences in these factors between hydrocephalus group and control group. After VPS was applied to treat the hydrocephalus patients, the patients recovered well in 30 d with normal temperature and without language dysfunction.

Conclusion

The high risk factors should be evaluated before the surgery of patients with TBI to prevent the complication of hydrocephalus. If there were, VPS is a suitable choice for the treatment.

表1 创伤性脑损伤患者开颅术前GCS和APACHEⅡ评分比较
表2 2组不同临床指标比较
表3 2组TBI术后患者疗效比较(±s
[1]
Ahmed S,Venigalla H,Mekala HM, et al. Traumatic Brain Injury and Neuropsychiatric Complications[J]. Indian J Psychol Med, 2017, 39(2): 114-121.
[2]
Carney N,Totten AM,O'Reilly C, et al. Guidelines for the management of severe traumatic brain Injury, fourth edition[J]. Neurosurgery, 2017, 80(1): 6-15.
[3]
江基尧,朱诚,罗其中.颅脑创伤救治指南[M].第3版.上海: 第二军医大学出版社, 2007: 222.
[4]
王雷平,吴崇光,姚军.颅脑损伤去骨瓣减压术后并发创伤后脑积水的危险因素[J].中华创伤杂志, 2014, 30(4): 307-310.
[5]
周良辅.负压和低压性脑积水[J].中华神经创伤外科电子杂志, 2016, 2(6): 321-327.
[6]
方黎晓,胡少玄,徐洪飞,等.侧脑室-腹腔分流术治疗外伤性脑积水术后并发症临床观察[J].中华神经创伤外科电子杂志, 2016, 2(1): 23-25.
[7]
Davanzo JR,Sieg EP,Timmons SD. Management of traumatic brain injury[J]. Surg Clin North Am, 2017, 97(6): 1237-1253.
[8]
Grandhi R,Bonfield CM,Newman WC, et al. Surgical management of traumatic brain injury: a review of guidelines, pathophysiology, neurophysiology, outcomes, and controversies[J]. J Neurosurg Sci, 2014, 58(4): 249-259.
[9]
Qvarlander S,Malm J,Eklund A. CSF dynamic analysis of a predictive pulsatility-based infusion test for normal pressure hydrocephalus[J]. Med Biol Eng Comput, 2014, 52(1): 75-85.
[10]
Vedantam A,Yamal JM,Hwang H, et al. Factors associated with shunt-dependent hydrocephalus after decompressive craniectomy for traumatic brain injury[J]. J Neurosurg, 2017, Epub ahead of print.
[11]
张寅,江毓敏,李永财.重型创伤性脑损伤患者发生脑积水的危险因素分析[J].宁夏医科大学学报, 2017, 39(2): 170-177.
[12]
Fotakopoulos G,Tsianaka E,Siasios G, et al. Posttraumatic hydrocephalus after decompressive craniectomy in 126 patients with severe traumatic brain injury[J]. J Neurol Surg A Cent Eur Neurosurg, 2016, 77(2): 88-92.
[13]
车彦军,夏智源,骆杰民,等.颅脑损伤后慢性脑积水和脑室扩张的危险因素及治疗策[J].中国实用神经疾病杂志, 2014, 17(22): 5-8.
[14]
Lee CN,Koh YC,Moon CT, et al. Serial mini-mental status examination to evaluate cognitive outcome in patients with traumatic brain injury[J]. Korean J Neurotrauma, 2015, 11(1): 6-10.
[15]
Korley FK,Diaz-Arrastia R,Wu AH, et al. Circulating brain-derived neurotrophic factor has diagnostic and prognostic value in traumatic brain injury[J]. J Neurotrauma, 2016, 33(2): 215-225.
[16]
叶建华.重型颅脑损伤患者并发脑积水的相关因素分析[J].实用医院临床杂志, 2014, 11(3): 83-85.
[17]
Kawoos U,Meng X,Huang SM, et al. Telemetric intracranial pressure monitoring in blast-induced traumatic brain injury[J]. IEEE Trans Biomed Eng, 2014, 61(3): 841-847.
[18]
Kim H,Lee HS,Ahn SY, et al. Factors associated postoperative hydrocephalus in patients with traumatic acute subdural Hemorrhage[J]. J Korean Neurosurg Soc, 2017, 60(6): 730-737.
[19]
Yan EB,Satgunaseelan L,Paul E, et al. Post-traumatic hypoxia is associated with prolonged cerebral cytokine production, higher serum biomarker levels, and poor outcome in patients with severe traumatic brain injury[J]. J Neurotrauma, 2014, 31(7): 618-629.
[20]
Kammersgaard LP,Linnemann M,Tibæk M. Hydrocephalus following severe traumatic brain injury in adults. Incidence, timing, and clinical predictors during rehabilitation[J]. NeuroRehabilitation, 2013, 33(3): 473-480.
[21]
黄国栋,李维平,黄贤键,等.神经内镜下和传统分流术治疗脑积水的疗效评价[J].中华神经医学杂志, 2010, 9(3): 308-311.
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