探讨高压氧治疗颅脑外伤的临床疗效。

选取爱德堡医院神经外科自2011年2月至2016年2月收治并确诊为颅脑外伤的患者492例，按入院顺序分为观察组（246例）和对照组（246例）。对照组采取常规治疗方式，观察组在常规治疗的基础上采取高压氧治疗。对比2组患者的临床疗效、认知功能水平和感染发生情况。

观察组治疗有效率为93.90%，明显高于对照组的78.86%，差异具有统计学意义（P<0.05）；2组治疗后语言、注意力及计算力、记忆力、回忆和定向力各项认知功能指标均比治疗前明显提高，观察组提高程度更明显，差异具有统计学意义（P<0.05）；观察组发生呼吸、血液、泌尿或其他系统感染的发生率为18.70%，显著低于对照组的42.28%，差异具有统计学意义（P<0.05）。

对颅脑外伤患者采用高压氧治疗，可获得更好的疗效，患者认知功能得到明显改善，且感染发生率低。高压氧治疗为颅脑外伤的有效治疗方法，值得推广应用。

To investigate the clinical efficacy of hyperbaric oxygen therapy in 492 patients with craniocerebral trauma.

Four hundred and ninety-two patients with craniocerebral trauma admitted in our hospital from February 2011 to February 2016 were divided into observation group (246 cases) and control group (246 cases) according to the order of admission. The control group was treated with conventional therapy, and the observation group was treated with hyperbaric oxygen on the basis of the control group. The clinical efficacy, cognitive function and infection were compared between the two groups.

The effective rate of the observation group was 93.90%, which was significantly higher than that of the control group (78.86%, P<0.05). The cognitive function index, memory, memory and recall were significantly higher in the two groups after treatment (P<0.05). The incidence of respiratory, blood, urinary or other systemic infections in the observation group was 18.70%, which was significantly lower than that of the control group (42.28%) (P<0.05).

Hyperbaric oxygen therapy in patients with craniocerebral trauma can achieve better therapeutic effect, and the cognitive function of patients is significantly improved, and the incidence of infection is low. Hyperbaric oxygen therapy for the effective treatment of craniocerebral trauma, it is worth promoting the application.