To investigate the efficacy and safety of interventional embolization at different time in the treatment of Hunt-Hess Ⅳ-Ⅴ grade intracranial aneurysm.

One hundred and twenty cases of Hunt Hess Ⅳ-Ⅴ intracranial aneurysm bleeding from January 2016 to January 2018 were selected and treated in the Department of Interventional, Huanggang Central Hospital. According to the time of intervention, they were divided into early group (<48 h), middle group (2-14 d) and late group (>14 d), 40 cases in each group. Three groups of patients were treated with embolization, the treatment, safety and recovery of the 3 groups were compared.

There was no significant difference among the 3 groups in the effective rate of interventional embolization (P>0.05). The incidence of adverse reactions in the 3 groups was statistically significant (P<0.05), the early group was the best, the middle group was the worse, and the late group was the worst. There was no significant difference in Barthel index score before treatment among the 3 groups (P>0.05). After treatment, the recovery of the 3 groups improved with the passage of time, and the recovery of the early group was the best, the late group was the worst.

Although the time of interventional embolization can not directly improve the therapeutic effect for patients with intracranial aneurysm bleeding, it can effectively improve the recovery speed of patients and reduce the incidence of adverse reactions.