Application of interventional therapy for 3D printing cerebral arteriovenous malformation model based on DICOM image fusion technology

doi:10.3877/cma.j.issn.2095-9141.2020.01.012

Abstract

Abstract:

Objective

To explore the clinical value of 3D printed cerebral arteriovenous malformation (AVM) model in interventional embolization therapy.

Methods

Retrospective collection of clinical data of patients with AVM who underwent interventional embolization at the Department of Neurosurgery, Zhongshan Hospital Affiliated to Dalian University from January 2016 to June 2019. Ten patients who were included in the preoperative routine imaging examination and constructed a 3D printed model were used as the test group, and 10 patients of the same level without the 3D printed model were used as the control group, to compare the size of the deformed vascular mass before and after embolization, the embolization rate, and the operation time etc.

Results

The difference in AVM size between the test group and its MRA/CTA was statistically significant (P<0.05). The average embolization rate of the test group was higher than that of the control group. The average difference of the area before and after embolization in the test group was significantly higher than that in the control group, and the average operation time was shorter than that in the control group (P<0.05). There was no significant difference in the AVM size between the test group and its DSA (P>0.05).

Conclusion

3D printing brain AVM model based on DICOM image fusion technology can display AVM anatomical structure features more directly and accurately, and has great clinical application value in clarifying AVM size, S-M classification, improving embolization effect and shortening operation time.

Key words: Cerebral arteriovenous malformation, Image fusion, 3D printing model, Interventional embolization

Pengcheng Li, Gang Ren, Jizhi Zhang, Mingwei Xu, Dongfeng Deng. Application of interventional therapy for 3D printing cerebral arteriovenous malformation model based on DICOM image fusion technology[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2020, 06(01): 49-52.

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References 15

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患者	年龄	性别	位置	栓塞前大小（cm²）	栓塞后大小（cm²）	差值（cm²）	栓塞率（%）	栓塞时间（min）
1	23	男	右颞叶	4.8×2.3	1.6×0.8	9.76	88.41	57
2	65	女	右顶叶	4.7×2.5	1.5×1.1	10.10	85.96	61
3	62	男	右枕叶	3.1×2.4	1.2×0.6	6.72	90.32	54
4	58	男	右枕叶	2.3×1.6	0	3.68	100.00	66
5	63	女	右额叶	4.7×3.3	1.4×1.3	13.69	88.27	74
6	42	女	右颞枕叶	3.3×2.1	0	6.93	100.00	65
7	21	女	左额叶	3.8×3.7	1.4×0.8	12.94	92.03	63
8	45	男	右额叶	3.6×3.5	1.8×1.2	10.44	82.86	64
9	36	男	左额叶	5.7×3.9	1.7×1.4	19.85	89.29	60
10	76	女	左小脑半球	2.8×2.6	0	7.28	100.00	72

患者	年龄	性别	位置	栓塞前大小（cm²）	栓塞后大小（cm²）	差值（cm²）	栓塞率（%）	栓塞时间（min）
1	23	男	右颞叶	4.8×2.3	1.6×0.8	9.76	88.41	57
2	65	女	右顶叶	4.7×2.5	1.5×1.1	10.10	85.96	61
3	62	男	右枕叶	3.1×2.4	1.2×0.6	6.72	90.32	54
4	58	男	右枕叶	2.3×1.6	0	3.68	100.00	66
5	63	女	右额叶	4.7×3.3	1.4×1.3	13.69	88.27	74
6	42	女	右颞枕叶	3.3×2.1	0	6.93	100.00	65
7	21	女	左额叶	3.8×3.7	1.4×0.8	12.94	92.03	63
8	45	男	右额叶	3.6×3.5	1.8×1.2	10.44	82.86	64
9	36	男	左额叶	5.7×3.9	1.7×1.4	19.85	89.29	60
10	76	女	左小脑半球	2.8×2.6	0	7.28	100.00	72

患者	年龄	性别	位置	栓塞前大小（cm²）	栓塞后大小（cm²）	差值（cm²）	栓塞率（%）	栓塞时间（min）
1	35	女	右额叶	2.8×2.8	1.2×1.1	6.52	83.16	68
2	52	男	左顶叶	3.1×2.6	1.5×1.1	6.41	79.53	65
3	64	男	右额叶	3.3×1.6	1.7×0.7	4.09	77.46	77
4	51	男	右小脑半球	3.4×2.1	1.4×1.0	5.74	80.39	69
5	40	男	右额叶	2.8×2.8	1.3×1.2	6.28	80.10	73
6	38	男	右颞枕叶	3.2×2.6	1.6×1.1	6.56	78.85	85
7	43	男	左额叶	3.3×1.6	1.4×0.7	4.30	81.44	73
8	61	女	右额叶	4.5×1.8	2.1×0.8	6.42	79.26	74
9	52	女	左额叶	2.7×2.2	0	5.94	100.00	64
10	48	女	左顶叶	3.8×2.4	1.8×1.2	6.96	76.32	78

患者	年龄	性别	位置	栓塞前大小（cm²）	栓塞后大小（cm²）	差值（cm²）	栓塞率（%）	栓塞时间（min）
1	35	女	右额叶	2.8×2.8	1.2×1.1	6.52	83.16	68
2	52	男	左顶叶	3.1×2.6	1.5×1.1	6.41	79.53	65
3	64	男	右额叶	3.3×1.6	1.7×0.7	4.09	77.46	77
4	51	男	右小脑半球	3.4×2.1	1.4×1.0	5.74	80.39	69
5	40	男	右额叶	2.8×2.8	1.3×1.2	6.28	80.10	73
6	38	男	右颞枕叶	3.2×2.6	1.6×1.1	6.56	78.85	85
7	43	男	左额叶	3.3×1.6	1.4×0.7	4.30	81.44	73
8	61	女	右额叶	4.5×1.8	2.1×0.8	6.42	79.26	74
9	52	女	左额叶	2.7×2.2	0	5.94	100.00	64
10	48	女	左顶叶	3.8×2.4	1.8×1.2	6.96	76.32	78

患者	MRA/CTA		3D虚拟图像		DSA
患者	大小（cm²）	S-M分级	大小（cm²）	S-M分级	大小（cm²）	S-M分级
1	4.6×2.0	Ⅲ级	4.8×2.3	Ⅲ级	4.8×2.2	Ⅲ级
2	4.4×2.2	Ⅲ级	4.7×2.5	Ⅲ级	4.6×2.6	Ⅲ级
3	2.8×2.2	Ⅱ级	3.1×2.4	Ⅲ级	3.2×2.4	Ⅲ级
4	1.9×1.3	Ⅲ级	2.3×1.6	Ⅲ级	2.3×1.6	Ⅲ级
5	4.5×3.1	Ⅲ级	4.7×3.3	Ⅲ级	4.6×3.2	Ⅲ级
6	2.9×1.8	Ⅱ级	3.3×2.1	Ⅲ级	3.3×2.1	Ⅲ级
7	3.5×3.5	Ⅲ级	3.8×3.7	Ⅲ级	3.8×3.6	Ⅲ级
8	3.4×3.2	Ⅲ级	3.6×3.5	Ⅲ级	3.6×3.5	Ⅲ级
9	6.2×4.1	Ⅳ级	5.7×3.9	Ⅲ级	5.6×3.8	Ⅲ级
10	2.5×2.3	Ⅲ级	2.8×2.6	Ⅲ级	2.8×2.7	Ⅲ级

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