Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Neurotraumatic Surgery(Electronic Edition) ›› 2020, Vol. 06 ›› Issue (03): 145-150. doi: 10.3877/cma.j.issn.2095-9141.2020.03.004

Special Issue:

• Clinical Research • Previous Articles     Next Articles

Analysis of clinical factors related to early prognosis of patients with intracranial ruptured aneurysm treated by interventional embolization

Chuanyu Li1, Weiwei Xu2, Cuicui Wei3, Haineng Huang1, Huadong Huang1, Qisheng Luo1, Kunxiang Luo1, Chengjian Qin1, Xueyu Li1, Chuanhua Zheng1, Chuanliu Lan1, Xiangyu Wang2,()   

  1. 1. Department of Neurosurgery, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China
    2. Department of Neurosurgery, The First Affiliated Hospital of Ji’nan University, Guangzhou 510000, China
    3. Department of Hand and Foot Surgery, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China
  • Received:2020-04-03 Online:2020-06-15 Published:2020-06-15
  • Contact: Xiangyu Wang
  • About author:
    Corresponding author: Wang Xiangyu, Email:

Abstract:

Objective

To analyze the related clinical factors with the prognosis of patients with intracranial ruptured aneurysm treated with endovascular interventional embolization.

Methods

The clinical data of 180 patients were consecutively collected from January 2014 to June 2018 in The Affiliated Hospital of Youjiang Medical University for Nationalities underwent intravascular interventional embolization of ruptured intracranial aneurysms. According to the modified rankin scale score at 1 month after bleeding, the patients were divided into the group with good prognosis (0-2 points) and the group with poor prognosis (3-6 points). Univariate analysis and multivariate Logistic regression analysis were used to screen out independent risk factors affecting poor prognosis of patients.

Results

Univariate analysis and multivariate Logistic regression analysis showed that World Federation of Neurological Surgeons Scale (WFNSS) classification at admission (OR=11.017, 95%CI: 4.153-29.229), cerebral infarction (OR=10.325, 95%CI: 2.060-51.740), intraoperative complications (OR=6.917, 95%CI: 1.493-32.052) and acute obstructive hydrocephalus (OR=6.685, 95%CI: 2.171-20.587) were independent risk factors for poor prognosis at 1 month. The area under curve of receiver operating curve showed that acute obstructive hydrocephalus 0.768 (95%CI: 0.689-0.846); WFNSS typing at admission 0.741 (95%CI: 0.661-0.821), cerebral infarction 0.658 (95%CI: 0.571-0.746), intraoperative complications: 0.609 (95%CI: 0.520-0.698).

Conclusion

It is demonstrated that the WFNSS of patients at admission plays a major role in the prognostic factors of patients and especially cerebral infarction is the most important independent risk factor affecting the prognosis. Clinical treatment should focus on how to reduce complications such as rehemorrhage after embolization, cerebral infarction and hydrocephalus, to reduce the death rate and disability rate of patients, and to improve the prognosis of patients.

Key words: Intracranial ruptured aneurysm, Subarachnoid hemorrhage, Interventional embolization

京ICP 备07035254号-20
Copyright © Chinese Journal of Neurotraumatic Surgery(Electronic Edition), All Rights Reserved.
Tel: 010-64229160 E-mail: zhsjcswk2015@163.com
Powered by Beijing Magtech Co. Ltd