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Chinese Journal of Neurotraumatic Surgery(Electronic Edition) ›› 2016, Vol. 02 ›› Issue (04): 206-209. doi: 10.3877/cma.j.issn.2095-9141.2016.04.004

Special Issue:

• Clinical Research • Previous Articles     Next Articles

Treatment strategy of hydrocephalus associated with intracranial infection

Zhao Song1, Xiaoyu Xia1, Yi Yang1, Ruxiang Xu1, Yongge Xu1,()   

  1. 1. Department of Neurosurgery, Shenzhen hospital of Southern Medical University, Shenzhen 518100, China; The Affiliated Bayi Brain Hospital, The PLA Army General Hospital, Beijing 100700, China
  • Received:2016-03-15 Online:2016-08-15 Published:2016-08-15
  • Contact: Yongge Xu
  • About author:
    Corresponding author: Xu Yongge, Email:

Abstract:

Objective

To explore the treatment strategy of hydrocephalus associated with intracranial infection.

Method

To choose 18 patients with hydrocephalus associated with intracranial infection, in the affiliated Bayi Brain Hospital, The PLA Army General Hospital between January 2011 and August 2014. Of which 15 cases need for cerebrospinal fluid drainage, 3 cases need lumbar puncture intermittently in order to control intracranial pressure, 10 cases with mild to moderate infection only be treated with antibiotic by simple intravenous ways, 8 severe cases with both intraventricular injection and intravenous methods. After infection was controlled, 6 cases were treated by ETV, 11 cases were treated by shunt operation and 1 cases gave up treatment.To contrast the number of days of infection controlled, double infection incidence and overall incidence of complications of two groups,SPSS 16.0 statistical analysis software was applled to analyze datas. Measurement data and the count data was expressed with mean+standard deviation (±s) and rate seperatelly. Rates were compared using chi square test, if P<0.05, the difference had statistically significant.

Results

After the infection was controlled, 6 cases underwent ETV operations, 11 cases underwent shunt operations, 1 case of abandoning treatment. The endoscopic treatment groups controlled infection in average(14.6±1.7) days, double infection rate was 0, the incidence of postoperative complications was 33.33%, shunt treatment group controlled infection in average (22.3±3.4) days, double infection rate was 18.2%, the incidence of postoperative complications was 45.45%. There were obvious difference in the number of days before the infection was controlled,and double infection rate between endoscopic treatment group and shunt treatment groups (P<0.05) .The incidence of postoperative complications was no significant difference between the two groups (P>0.05) .

Conclusion

Hydrocephalus associated with intracranial infection had more complications and was difficult to treate.Endoscopic sugery had more superiority in controlling infection, avoiding double infection incidence. Endoscopic surgery should be selected as the first treatment for hydrocephalus associated with intracranial infection.

Key words: Hydrocephalus, Intracranial infection, Neural endoscopy

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