Abstract:
Objective
To compare the curative effects of two intensive insulin therapies with different blood glucose target on patients with stress hyperglycemia after craniocerebral trauma.
Methods
Fifty-six traumatic patients enrolled from January 2010 to October 2014 were divided randomly in two groups with different blood glucose targets:4.4～6.1mmol/L in the low-target group(Leuven Method)and 6.2～8.9mmol/L in the high～target group.
Results
The mortality rates,incidence of MOF,duration in ICU and Infection incidences of the two groups have no significant difference,and the incidence of hypoglycemia is low in high-target group.
Conclusions
There is no significant difference in the two group of target-valued intensive insulin therapy methods as far as preliminary clinical curative effect is concerned.Because the incidence of hypoglycemia is high in low-target group,the high-target-valued method is more suitable for clinical appliance.
Key words:
Insulin,
Hyperglycemia,
Crainocerebral trauma
Jie Yan, Yipeng Zhang, Hong Li, Baohai Feng, Jianjun Yang, Guishui Wang. Effect of intensive insulin therapy on patients with stress hyperglycemia after craniocerebral trauma[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2015, 01(04): 216-218.