Research progress of neural stem cells with estrogen treating on traumatic brain injury

doi:10.3877/cma.j.issn.2095-9141.2020.06.011

Abstract

Abstract:

It is well known that estrogen is a very important signal molecule in the nervous system. In recent years, studies have proved that estrogen has a promoting effect on the growth and development, proliferation as well as differentiation of neural stem cells (NSCs), which having a controlling effect on the direction of their differentiation. There have also been numerous experimental studies on the treatment of traumatic brain injury (TBI) by NSCs transplantation, indicating that the level of NSCs is closely related to the recovery degree and prognosis of TBI. In order to elaborate on the latest findings, the authors will review the effects of estrogen on the control and differentiation of NSCs, as well as the clinical application of NSCs transplantation in the treatment of TBI.

Key words: Traumatic brain injury, Neural stem cell, Estrogen

Yuting Liang, Yue Hu, Anqi Zhao, Murong Wang, Jian Sun, Lizhuo Li. Research progress of neural stem cells with estrogen treating on traumatic brain injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2020, 06(06): 373-376.

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