Clinical study of using Yangxueqingnao granule to improve cognitive function of convalescent patients with hypertensive cerebral hemorrhage after operation

doi:10.3877/cma.j.issn.2095-9141.2017.04.007

Abstract

Abstract:

Objective

To evaluate the clinical therapeutic efficacy of using Yangxueqingnao granule to improve cognitive function of convalescent patients with hypertensive cerebral hemorrhage after operation.

Methods

Sixty patients in the medical center of dujiangyan city from October 2009 to February 2011 were divided randomly into two groups. The treat group underwent yangxueqingnao granule and the control group received conventional therapy. The pre-therapy and post-therapy patients’status were assessed by mini mental state examination(MMSE) and Barhtel index(BI).

Results

The scores of MMSE and BI increase significantly in treating group after treatment, compared with those before t reatment (P<0.05). No complications were observed.

Conclusion

Yangxueqingnao granule is a kind of safe and effective Chinese patent medicine, it can treat nervous dysfunction induced by hypertensive cerebral hemorrhage after operation, it can accelerate functional rehabilitation and improve the quality of life of patients. So it can be used extensively in clinic.

Key words: Yangxueqingnao granule, Hypertensive cerebral hemorrhage, Cognitive handicap

Yong Yi, Zhangming Zhou. Clinical study of using Yangxueqingnao granule to improve cognitive function of convalescent patients with hypertensive cerebral hemorrhage after operation[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2017, 03(04): 218-220.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhsjcswkdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-9141.2017.04.007

https://zhsjcswkdzzz.cma-cmc.com.cn/EN/Y2017/V03/I04/218

组别	例数	MMSE评分（分）			时间比较
组别	例数	治疗前	治疗后1个月	治疗后3个月	F值	P值
治疗组	30	12.59±1.65	18.96±1.39^a	25.05±1.51^a	36.670	<0.05
对照组	30	13.28±2.08	15.33±1.51	17.54±2.25	36.670	<0.05
组间比较	?	F=29.430，P<0.05			?	?

组别	例数	MMSE评分（分）			时间比较
组别	例数	治疗前	治疗后1个月	治疗后3个月	F值	P值
治疗组	30	12.59±1.65	18.96±1.39^a	25.05±1.51^a	36.670	<0.05
对照组	30	13.28±2.08	15.33±1.51	17.54±2.25	36.670	<0.05
组间比较	?	F=29.430，P<0.05			?	?

组别	例数	MMSE评分（分）			时间比较
组别	例数	治疗前	治疗后1个月	治疗后3个月	F值	P值
治疗组	30	68.72±3.22	80.76±3.05^a	91.31±4.39^a	49.690	<0.05
对照组	30	70.05±2.57	73.21±2.50	76.33±2.85	49.690	<0.05
组间比较	?	F=41.230，P<0.05			?	?

组别	例数	MMSE评分（分）			时间比较
组别	例数	治疗前	治疗后1个月	治疗后3个月	F值	P值
治疗组	30	68.72±3.22	80.76±3.05^a	91.31±4.39^a	49.690	<0.05
对照组	30	70.05±2.57	73.21±2.50	76.33±2.85	49.690	<0.05
组间比较	?	F=41.230，P<0.05			?	?

[1]	龚立，王静予，孔令军,等.祛瘀化痰通腑法治疗高血压脑出血术后患者的临床观察[J].上海中医药大学学报, 2015, 29(4): 24-26.
[2]	王永谦，施杞，王维平,等.血府逐瘀汤口服液治疗高血压性脑出血的临床研究[J].中国中医急症, 2013, 22(10): 1686-1687.
[3]	楼小亮，席秋江，胡雪勇,等.养血清脑颗粒对大鼠脑缺血再灌注损伤后神经干细胞增殖分化的影响[J].中国神经精神疾病杂志, 2014, 40(7): 394-399.
[4]	雷小峰，赵佩，牛争平,等.养血清脑颗粒对硝酸甘油偏头痛模型大鼠三叉神经脊束核c-Fos蛋白表达的影响[J].中国现代神经疾病杂志, 2014, 14(8): 708-716.
[5]	朱晓丽，张宁.养血清脑颗粒联合氟桂利嗪治疗偏头痛的疗效观察[J].中国实用神经疾病杂志, 2015, 18(24): 128-129.
[6]	孙微，王策，刘佳乐,等.养血清脑颗粒联合强力定眩片对慢性脑供血不足患者认知功能的影响[J].中国老年学杂志, 2014, (14): 3841-3843.

Please choose a citation manager

Content to export