Clinical research of serum Myelin basic protein change in the hypothermia treatments for severe hemorrhage

doi:10.3877/cma.j.issn.2095-9141.2018.02.009

Abstract

Abstract:

Objective

To discuss the effect of hypothermia treatment on serum MBP in patients with severe hypertensive cerebral hemorrhage.

Methods

Sixty-four cases of severe hypertensive cerebral hemorrhage (GCS<9) were randomly divided into control group (n=32) and hypothermia group (n=32). Control group received routine treatment, hypothermia group were up in the routine treatment of hypothermia treatment. The scores of GCS and the levers of serum MBP which were detected before and after the treatment in both groups were compared.

Results

The scores of GCS in the hypothermia group were significantly higher than those in the control group respectively. The levers of serum MBP were all increased in both groups after fall in as compared with normal controls. The increased serum MBP’s levers were dropped significantly after treatment in both groups as compared with those before treatment but the levels of serum MBP were lower obviously in hypothermia group than in control group.

Conclusion

The level of serum MBP is important for estimating the effectives of hypothermia treatment in patients with hypertensive.

Key words: Hypothermia, Hypertensive cerebral hemorrhage, Myelin basic protein

Wei Qiu, Na Huang, Zhiwang Guo, Huimin Chang. Clinical research of serum Myelin basic protein change in the hypothermia treatments for severe hemorrhage[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2018, 04(02): 103-105.

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References 20

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分组	例数	治疗前（起病3 h）	治疗后
分组	例数	治疗前（起病3 h）	1d	3d	7d	10 d
亚低温组	32	9.0±3.4	8.9±3.5	9.8±4.2	12.1±3.0	12.7±3.3
常规组	32	8.9±3.6	9.0±3.5	9.7±4.1	10.2±4.0	10.9±4.2
P值	?	3.124	5.110	3.133	0.012	0.023

分组	例数	治疗前（起病3 h）	治疗后
分组	例数	治疗前（起病3 h）	1d	3d	7d	10 d
亚低温组	32	9.0±3.4	8.9±3.5	9.8±4.2	12.1±3.0	12.7±3.3
常规组	32	8.9±3.6	9.0±3.5	9.7±4.1	10.2±4.0	10.9±4.2
P值	?	3.124	5.110	3.133	0.012	0.023

分组	例数	治疗前（起病3 h）	治疗后
分组	例数	治疗前（起病3 h）	1d	3d	7d	10 d
亚低温组	32	2.2±0.6	7.7±2.4	8.6±2.6	7.6±2.1	3.0±1.3
常规组	32	2.1±0.7	7.8±2.4	8.5±2.7	8.1±1.9	5.0±2.6
P值	?	4.257	3.127	4.222	0.003	0.031

分组	例数	治疗前（起病3 h）	治疗后
分组	例数	治疗前（起病3 h）	1d	3d	7d	10 d
亚低温组	32	2.2±0.6	7.7±2.4	8.6±2.6	7.6±2.1	3.0±1.3
常规组	32	2.1±0.7	7.8±2.4	8.5±2.7	8.1±1.9	5.0±2.6
P值	?	4.257	3.127	4.222	0.003	0.031

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