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中华神经创伤外科电子杂志

中华神经创伤外科电子杂志 ›› 2021, Vol. 07 ›› Issue (06) : 372 -375. doi: 10.3877/cma.j.issn.2095-9141.2021.06.011

综述

与视器相关的无创颅内压监测
何鑫1, 武秀权1, 费舟1, 费霏2,†()   
  1. 1. 710032　西安，空军军医大学第一附属医院神经外科
    2. 710032　西安，空军军医大学第一附属医院眼科
  • 收稿日期:2021-08-27 出版日期:2021-12-15
  • 通信作者: 费霏

Visual organs related noninvasive intracranial pressure monitoring

Xin He1, Xiuquan Wu1, Zhou Fei1, Fei Fei2,†()   

  1. 1. Department of Neurosurgery, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, China
    2. Department of Ophthalmology, The First Affiliated Hospital of Air Force Medical University, Xi’an 710032, China
  • Received:2021-08-27 Published:2021-12-15
  • Corresponding author: Fei Fei
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何鑫, 武秀权, 费舟, 费霏. 与视器相关的无创颅内压监测[J]. 中华神经创伤外科电子杂志, 2021, 07(06): 372-375.

Xin He, Xiuquan Wu, Zhou Fei, Fei Fei. Visual organs related noninvasive intracranial pressure monitoring[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2021, 07(06): 372-375.

重型颅脑损伤后颅内压（ICP）增高发生率高，其监测对于临床有效治疗和预后判断具有重要的意义。临床上ICP的监测方法可分为有创和无创两类，虽然目前以有创ICP监测为主，但无创ICP监测一直是科学家们探索和追求的目标。本文主要针对4种与视器相关的无创ICP监测方法如视神经鞘直径、眼内压、闪光视觉诱发电位和光学相干断层成像的研究进展作一综述，比较不同无创ICP监测方法的原理、应用现状和优劣势，为拓展无创ICP监测新方法、优化神经重症患者的早期诊断和治疗提供思路。

关键词: 颅内压, 视器, 无创监测

The incidence of increased intracranial pressure (ICP) after severe head injury is high, and its monitoring is of great significance for effective clinical treatment and prognosis judgment. Clinical monitoring methods of ICP can be divided into two categories: invasive and non-invasive. Although invasive ICP monitoring is currently the main method, non-invasive ICP monitoring has always been the goal of scientists to explore and pursue. This article mainly expounds four visual organs related ICP noninvasive monitoring methods including the optic nerve sheath diameter, intraocular pressure, flash visual evoked potentials, optical coherence tomography and their research progress, and compares the principles, application statuses, advantages and limitations of different noninvasive ICP monitoring methods in order to provide new idea for the development of a new method for noninvasive ICP monitoring, and for the optimization of the early diagnosis and treatment of severe head injured patients.

Key words: Intracranial pressure, Visual organs, Noninvasive monitoring
表1 部分研究判定颅内压增高的视神经鞘直径临界值
作者 年份 国家 样本量 ONSD临界值（mm）
Geeraerts等[14] 2007 法国 31 5.9
Bäuerle等[15] 2011 德国 35 5.8
Siranović等[16] 2011 克罗地亚 26 6.1
Caffery等[7] 2014 美国 51 5.5
Sekhon等[17] 2014 加拿大 57 6.0
Wang等[8] 2015 中国 279 4.1
Maissan等[18] 2015 荷兰 18 5.0
Nash等[19] 2016 美国 20 5.0
Raffiz和Abdullah[6] 2017 马来西亚 41 5.2
Jeon等[9] 2017 韩国 62 5.6
Liu等[13] 2017 中国 110 5.6
Soliman等[20] 2018 沙特阿拉伯 40 6.4
Chen等[21] 2019 中国 165 4.1
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