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中华神经创伤外科电子杂志 ›› 2018, Vol. 04 ›› Issue (01) : 9 -12. doi: 10.3877/cma.j.issn.2095-9141.2018.01.003

所属专题: 文献

临床研究

ICU重型颅脑损伤患者行血管内控制性降温治疗的疗效分析
刘静1, 易波1, 李保林1,()   
  1. 1. 450007 郑州,郑州大学附属郑州中心医院重症医学科
  • 收稿日期:2017-08-31 出版日期:2018-02-15
  • 通信作者: 李保林
  • 基金资助:
    郑州市科技攻关项目(131PPTGG390)

Effect of intravascular controlled cooling on ICU patients with severe traumatic brain injury

Jing Liu1, Bo Yi1, Baolin Li1,()   

  1. 1. Intensive Care Unit, Zhenzhou Central Hospital Affiliated to Zhenzhou University, Zhenzhou 450007, China
  • Received:2017-08-31 Published:2018-02-15
  • Corresponding author: Baolin Li
  • About author:
    Corresponding author: Li Baolin, Email:
引用本文:

刘静, 易波, 李保林. ICU重型颅脑损伤患者行血管内控制性降温治疗的疗效分析[J/OL]. 中华神经创伤外科电子杂志, 2018, 04(01): 9-12.

Jing Liu, Bo Yi, Baolin Li. Effect of intravascular controlled cooling on ICU patients with severe traumatic brain injury[J/OL]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2018, 04(01): 9-12.

目的

探讨血管内降温治疗对重型颅脑损伤患者意识水平、脑氧代谢和颅内压(ICP)的影响。

方法

选取2015年4月至2017年4月郑州大学附属郑州中心医院重症医学科收治的重型颅脑损伤术后患者100例,按照随机数字表法分为对照组和观察组,每组50例。对照组给予常规标准化治疗,观察组给予血管内降温治疗。观察并比较2组患者治疗前、治疗3 d后意识水平、ICP、脑氧代谢变化。

结果

2组患者治疗后的意识水平、ICP、脑氧代谢等指标水平均较同组治疗前均显著提高,差异有统计学意义(P<0.05),且治疗后观察组水平均显著高于对照组,差异有统计学意义(P<0.05)。

结论

血管内降温治疗能明显改善重型颅脑损伤患者的意识水平,提高脑氧代谢水平,同时降低ICP,具有重要的临床实践价值。

Objective

To investigate the effect of intravascular cooling therapy on mean level, cerebral oxygen metabolism and intracranial pressure (ICP) in patients with severe traumatic brain injury.

Methods

From April 2015 to April 2017, 100 patients with severe traumatic brain injury were enrolled in the Intensive Care Unit of Zhengzhou Central Hospital Affiliated to Zhengzhou University. According to the random data table method, the patients were divided into control group and observation group. The control group was given routine standardized treatment, the observation group given intravascular cooling treatment. The changes of consciousness, ICP and cerebral oxygen metabolism were observed before and after 3 d of treatment.

Results

The level of consciousness, ICP and cerebral oxygen metabolism were significantly higher in the two groups than in the same group (P<0.05), and the level of the observation group (P<0.05).

Conclusion

Intravascular cooling therapy can significantly improve the consciousness level of patients with severe traumatic brain injury, improve the level of cerebral oxygen metabolism, and reduce the ICP, which is of great significance clinical practice value.

表1 2组治疗前后GCS评分变化对比(±s
表2 2组患者治疗前后颅内压水平比较(±s
表3 2组患者治疗前后动脉血氧分压、血氧饱和度指标比较(±s
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