Neurosurgical therapeutic strategies for diabetic foot

doi:10.3877/cma.j.issn.2095-9141.2025.04.001

Abstract

Abstract:

Diabetic foot ulceration and deep tissue destruction result from concurrent lower-limb neurological and vascular damage in patients with diabetes mellitus, imposing a substantial burden on health and quality of life. Conventional medical strategies that focus on metabolic control and hemodynamic improvement offer limited benefit for refractory ulcers dominated by diabetic peripheral neuropathy, making surgical intervention essential. Neurosurgical techniques provide an individualized approach for different pathogenic subtypes through decompression of entrapped nerves, spinal cord stimulation for analgesia and microcirculatory enhancement, and comprehensive wound care. This review summarizes current clinical classification, differential diagnostic considerations, and neurosurgical treatment principles, emphasizing the value of multidisciplinary collaboration and neuromodulation technology in optimizing integrated management of diabetic foot.

Key words: Diabetic foot, Diabetic peripheral neuropathy, Nerve decompression, Spinal cord stimulation, Neuromodulation

Li Zhang. Neurosurgical therapeutic strategies for diabetic foot[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2025, 11(04): 205-209.

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