Research progress in drug therapy targeting neuroinflammation in traumatic brain injury

doi:10.3877/cma.j.issn.2095-9141.2025.03.001

Abstract

Abstract:

Traumatic brain injury (TBI) is one of the leading causes of disability and death among young people, resulting in acute or permanent damage to physical, psychological, and cognitive functions. Currently, the treatment for TBI primarily involves surgical decompression and symptomatic supportive care, with a lack of effective interventions targeting the underlying pathological mechanisms. Recent studies have confirmed that neuroinflammation plays a crucial role in the pathophysiological process of TBI, and strategies targeting neuroinflammation hold promise for providing new pathways for TBI. This review aims to discuss the progress in drug therapies targeting neuroinflammation in TBI, with the goal of providing reference for future research.

Key words: Traumatic brain injury, Neuroinflammation, Treatment strategies

Yuyang Liu, Yaping Feng. Research progress in drug therapy targeting neuroinflammation in traumatic brain injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2025, 11(03): 137-143.

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