Recent advances in the treatment of post-traumatic epilepsy

doi:10.3877/cma.j.issn.2095-9141.2016.01.010

Abstract

Abstract:

Post-traumatic epilepsy (PTE) is a recurrent seizure disorder secondary to traumatic brain injury (TBI). Its pathogenesis is complex, while patients have different treatment effects. The purpose of this study is to focus on recent advances in understanding of modeling and clinical medical of post-traumatic epilepsy (PTE), establishing reference values for clinical use.

Key words: Post-traumatic epilepsy, Traumatic brain injury, Animal model

Zunbin Ke, Zhirong Yang, Yigang Yu. Recent advances in the treatment of post-traumatic epilepsy[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2016, 02(01): 37-40.

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https://zhsjcswkdzzz.cma-cmc.com.cn/EN/Y2016/V02/I01/37

References 40

[1]	Carod-Artal FJ,Vargas AP,Mesquita HM. Aetiology of epileptic seizures in a rehabilitation centre[J]. Rev Neurol, 2009, 49(7): 349-353.
[2]	Szaflarski JP,Nazzal Y,Dreer LE. Post-traumatic epilepsy: current and emerging treatment options[J]. Neuropsychiatri Dis Treat, 2014, 10: 1469-1477.
[3]	Klimek M,Dammers R. Antiepileptic drug therapy in the perioperative course of neurosurgical patients[J]. Curr Opin Anesthesiol, 2010, 23(5): 564-567.
[4]	Hunt RF,Boychuk JA,Smith BN. Neural circuit mechanisms of post-traumatic epilepsy[J]. Front Cell Neurosci, 2013, 7: 89.
[5]	Sanchez Mejia RO,Ona VO,Li M, et al. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction[J]. Neurosurgery, 2001, 48(6): 1393-1399.
[6]	Jordan J,Fernandez-Gomez FJ,Ramos M, et al. Minocycline and cytoprotection: shedding new light on a shadowy controversy[J]. Curr Drug Deliv, 2007, 4(3): 225-231.
[7]	Heo K,Cho YJ,Cho KJ, et al. Minocycline inhibits caspase-dependent and-independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice[J]. Neurosci Lett, 2006, 398(3): 195-200.
[8]	Lu DC,Zador Z,Yao J, et al. Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice[J]. J Neurotrauma, 2011, 09.
[9]	Abraham J,Fox PD,Condello C, et al. Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures[J]. Neurobiol Dis, 2012, 46(2): 425-430.
[10]	Singh M,Su C. Progesterone, brain-derived neurotrophic factor and neuroprotection[J]. Neuroscience, 2013, 239(6): 84-91.
[11]	Gibson CL,Gray LJ,Bath PM, et al. Progesterone for the treatment of experimental brain injury; a systematic review[J]. Brain, 2008, 131(Pt 2): 318-328.
[12]	Diamond ML,Ritter AC,Failla MD, et al. IL-1beta associations with posttraumatic epilepsy development: A genetics and biomarker cohort study[J]. Epilepsia, 2015, 56(7): 991-1001.
[13]	Zou H,Brayer SW,Hurwitz M, et al. Neuroprotective, neuroplastic, and neurobehavioral effects of daily treatment with levetiracetam in experimental traumatic brain injury[J]. Neurorehabil Neural Repair, 2013, 27(9): 878-888.
[14]	Dietrich WD,Bramlett HM. The evidence for hypothermia as a neuroprotectant in traumatic brain injury[J]. Neurotherapeutics, 2010, 7(1): 43-50.
[15]	Fritz HG,Bauer R. Secondary injuries in brain trauma: effects of hypothermia[J]. J Neurosurg Anesthesiol, 2004, 16(1): 43-52.
[16]	D′Ambrosio R,Eastman CL,Fattore C, et al. Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation[J]. Expert Rev Neurother, 2013, 13(6): 615-625.
[17]	Raible DJ,Frey LC,Del Angel YC, et al. JAK/STAT pathway regulation of GABAA receptor expression after differing severities of experimental TBI[J]. Exp Neurol, 2015, 271: 445-456.
[18]	Dinocourt C,Gallagher SE,Thompson SM. Injury-induced axonal sprouting in the hippocampus is initiated by activation of trkB receptors[J]. Eur J Neurosci, 2006, 24(7): 1857-1866.
[19]	Wilson SM,Xiong W,Wang Y, et al. Prevention of posttraumatic axon sprouting by blocking collapsin response mediator protein 2-mediated neurite outgrowth and tubulin polymerization[J]. Neuroscience, 2012, 210: 451-466.
[20]	Weston J,Greenhalgh J,Marson AG. Antiepileptic drugs as prophylaxis for post-craniotomy seizures[J]. Cochrane Database Syst Rev, 2015, 3: D7286.
[21]	Bhattacharyya K,Mandal N,Paul UK, et al. Post-traumatic seizure: a multicentric epidemiological study[J]. J Indian Med Assoc, 2014, 112(2): 93-95.
[22]	江基尧,张浚,李维平,等.抗癫痫药预防外伤性癫痫的多中心临床研究[J].中华神经外科疾病研究杂志, 2004(04): 301-303.
[23]	Rao VR,Parko KL. Clinical approach to posttraumatic epilepsy[J]. Semin Neurol, 2015, 35(1): 57-63.
[24]	Translational Research in Traumatic Brain Injury[M]. Boca Raton (FL): CRC Press/Taylor and Francis Group, 2016.
[25]	Rinaldi A,Conti L. Posttraumatic epilepsy[J]. Neurol Sci, 2003, 24(4): 229-230.
[26]	金保哲,袁国艳,张新中,等.功能区外伤性癫痫的手术治疗[J].中国综合临床, 2010, 26(6): 578-580.
[27]	史保中,郝晓伟,范波,等.外伤性癫痫的手术治疗[J].中华创伤杂志, 2009, 25(2): 116-119.
[28]	Hakimian S,Kershenovich A,Miller JW, et al. Long-term outcome of extratemporal resection in posttraumatic epilepsy[J]. Neurosurg Focus, 2012, 32(3): E10.
[29]	Englot DJ,Chang EF,Auguste KI. Efficacy of vagus nerve stimulation for epilepsy by patient age, epilepsy duration, and seizure type[J]. Neurosurg Clin N Am, 2011, 22(4): 443-448.
[30]	Englot DJ,Chang EF,Auguste KI. Vagus nerve stimulation for epilepsy: a meta-analysis of efficacy and predictors of response[J]. J Neurosurg, 2011, 115(6): 1248-1255.
[31]	Spuck S,Tronnier V,Orosz I, et al. Operative and technical complications of vagus nerve stimulator implantation[J]. Neurosurgery, 2010, 67(2 Suppl Operative): 489-494.
[32]	Lee HO,Koh EJ,Oh YM, et al. Effect of vagus nerve stimulation in post-traumatic epilepsy and failed epilepsy surgery: preliminary report[J]. J Korean Neurosurg Soc, 2008, 44(4): 196-198.
[33]	Ben-Menachem E,Krauss GL. Epilepsy: responsive neurostimulation-modulating the epileptic brain[J]. Nat Rev Neurol, 2014, 10(5): 247-248.
[34]	Heck CN,King-Stephens D,Massey AD, et al. Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial[J]. Epilepsia, 2014, 55(3): 432-441.
[35]	杨学旺,陈淳,朱太平,等.中西医结合治疗外伤性癫痫的疗效观察[J].中国临床神经外科杂志, 2011, 16(9): 560-561.
[36]	周文,谢泽宇,林开颜,等.高压氧治疗外伤性癫痫大鼠模型的机制[J].广东医学, 2015, (1): 60-62.
[37]	林开颜,李沐,谢泽宇,等.高压氧对外伤性癫痫动物模型的治疗作用[J].神经损伤与功能重建, 2014, (5): 382-384.
[38]	Silva LF,Hoffmann MS,Gerbatin RR, et al. Treadmill exercise protects against pentylenetetrazol-induced seizures and oxidative stress after traumatic brain injury[J]. J Neurotrauma, 2013, 30(14): 1278-1287.
[39]	D′Ambrosio R,Fairbanks JP,Fender JS, et al. Post-traumatic epilepsy following fluid percussion injury in the rat[J]. Brain, 2004,127(Pt 2): 304-314.
[40]	Cole J T,Yarnell A,Kean W S, et al. Craniotomy: true sham for traumatic brain injury, or a sham of a sham?[J]. J Neurotrauma, 2011,28(3): 359-369.

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