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Chinese Journal of Neurotraumatic Surgery(Electronic Edition) ›› 2020, Vol. 06 ›› Issue (03): 183-186. doi: 10.3877/cma.j.issn.2095-9141.2020.03.012

Special Issue:

• Review • Previous Articles     Next Articles

Application of IGF-1 in the diagnosis and treatment of pituitary tumor

Zhaowei Xu1, Rui Bai1, Hubin Duan1, Yimin Fan1,()   

  1. 1. Department of Neurosurgery, The First Hospital of Shanxi Medical University, Taiyuan 030000, China
  • Received:2019-10-17 Online:2020-06-15 Published:2020-06-15
  • Contact: Yimin Fan
  • About author:
    Corresponding author: Fan Yimin, Email:

Abstract:

Insulin-like growth factor-1 (IGF-1) and its receptor are components of the insulin-like growth factor system and play an important role in the development and evolution of tumors such as nervous system, respiratory system and digestive system. Through the intervention of the relationship between IGF-1 and its receptor and tumor evolution, it can provide help for the clinical diagnosis and treatment of tumors. Pituitary tumors are relatively common intracranial tumors. Studies have found that IGF-1 is expressed in pituitary tumors. This article describes the expression and application of IGF-1 and tumors in pituitary tumor.

Key words: Insulin-like growth factor-1, Tumor, Pituitary tumor, Acromegaly

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