To explore the selection of microsurgical approach for neurocytoma and the analysis of clinical treatment and clinical effect.

Thirty-three cases were treated by microsurgery from December 2011 to October 2019 in the First Department of Neurosurgery, Guangzhou 999 Brain Hospital. The clinical data of surgical approach selection, the key points of the surgery, the surgery related conditions of different surgical approaches and postoperative scores were analysis.

There were 20 cases treated by the approach of the superior frontal gyrus-lateral ventricle anterior horn, 10 cases treated by the approach of triangular-ventricular and 3 cases treated by the approach of the anterior longitudinal fissure-corpus callosum. Twenty-six cases were resected completely and 7 cases were resected subtotally. Two cases were treated by ventricular-abdominal shunt after operation, and 7 cases were received radiotherapy and chemotherapy. All cases were followed up for 6 months to 8 years, and no recurrence case was found. In the three surgical approaches, the difference between the operation time and the volume of bleeding was statistically significant (P<0.05); the operation time and the bleeding volume of the longitudinal fissure-corpus callosum approach was higher than those of the middle frontal gyrus approach and the triangle approach, the difference was statistically significant (P<0.05). Three months after operation, the Karnofsky scores in the three groups of patients were not significantly different (P>0.05).

According to the characteristics of the lesion, it may be helpful for the resection completely for the treatment of central neurocytoma in ventricle by choosing the appropriate surgical approach. Furthermore, it should improve the prognosis of patients by combination of radiotherapy and chemotherapy after surgery.