To evaluate the clinical effect and safety of neuro-endoscopy and keyhole micro-therapy using in basal ganglion hemorrhage.

Sixty two cases who were suffering from basal ganglion hemorrhage from Jan 1, 2015 to Dec 31, 2016 who were receiving treatment in Shunde Hospital of Southern Medical University were selected and divided into neuro-endoscopy group (n=35) and keyhole micro-therapy group (n=27) randomly. Then statistic and analysis the operation time, blood loss volume during operation, hematoma clearance rate, length of hospital stays and the other index of operation and complication occurrence rate, to compare the GCS variation before operation and 7 d after operation. After 6 months, comparing the prognosis between these two groups using activity of daily living scale.

The operation time and length of hospital stays are shorter, the blood loss volume is much less, and the hematoma clearance rate is higher, in neuro-endoscopy group than keyhole micro-therapy group significantly (P<0.05). The complication occurrence rate in neuro-endoscopy group is much less than keyhole micro-therapy group (5.71% vs. 29.63%) (P<0.05). Seven days after operation, the GCS status in neuro-endoscopy group is better than keyhole micro-therapy group significantly (P<0.05); 6 months after operation, the prognosis in neuro-endoscopy group is better than keyhole micro-therapy group significantly (P<0.05).

Comparing to keyhole micro-therapy, neuro-endoscopy could shorten operation time and length of hospital stays, reduce blood loss volume during operation, increase hematoma clearance rate, reduce complication occurrence rate when using in basal ganglion hemorrhage.