Effect of intravascular controlled cooling on ICU patients with severe traumatic brain injury

doi:10.3877/cma.j.issn.2095-9141.2018.01.003

Abstract

Abstract:

Objective

To investigate the effect of intravascular cooling therapy on mean level, cerebral oxygen metabolism and intracranial pressure (ICP) in patients with severe traumatic brain injury.

Methods

From April 2015 to April 2017, 100 patients with severe traumatic brain injury were enrolled in the Intensive Care Unit of Zhengzhou Central Hospital Affiliated to Zhengzhou University. According to the random data table method, the patients were divided into control group and observation group. The control group was given routine standardized treatment, the observation group given intravascular cooling treatment. The changes of consciousness, ICP and cerebral oxygen metabolism were observed before and after 3 d of treatment.

Results

The level of consciousness, ICP and cerebral oxygen metabolism were significantly higher in the two groups than in the same group (P<0.05), and the level of the observation group (P<0.05).

Conclusion

Intravascular cooling therapy can significantly improve the consciousness level of patients with severe traumatic brain injury, improve the level of cerebral oxygen metabolism, and reduce the ICP, which is of great significance clinical practice value.

Key words: Severe traumatic brain injury, Intravascular cooling, Curative effect

Jing Liu, Bo Yi, Baolin Li. Effect of intravascular controlled cooling on ICU patients with severe traumatic brain injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2018, 04(01): 9-12.

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References 20

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组别	例数	GCS评分		t值	P值
组别	例数	治疗前	治疗后	t值	P值
对照组	50	5.7±1.1	6.3±1.2	7.953	0.008
观察组	50	5.9±1.2	7.8±1.1	10.862	0.000
t值	?	0.302	9.129	?	?
P值	?	0.776	0.000	?	?

组别	例数	GCS评分		t值	P值
组别	例数	治疗前	治疗后	t值	P值
对照组	50	5.7±1.1	6.3±1.2	7.953	0.008
观察组	50	5.9±1.2	7.8±1.1	10.862	0.000
t值	?	0.302	9.129	?	?
P值	?	0.776	0.000	?	?

组别	例数	颅内压(mmHg)		t值	P值
组别	例数	治疗前	治疗后	t值	P值
对照组	50	16.04±3.11	14.78±3.22	7.891	0.001
观察组	50	15.99±3.21	11.47±3.16	11.262	0.000
t值	?	0.307	8.725	?	?
P值	?	0.297	0.000	?	?

组别	例数	颅内压(mmHg)		t值	P值
组别	例数	治疗前	治疗后	t值	P值
对照组	50	16.04±3.11	14.78±3.22	7.891	0.001
观察组	50	15.99±3.21	11.47±3.16	11.262	0.000
t值	?	0.307	8.725	?	?
P值	?	0.297	0.000	?	?

组别	例数	动脉血氧分压				血氧饱和度
组别	例数	治疗前	治疗后	t值	P值	治疗前	治疗后	t值	P值
对照组	50	74.58±16.44	90.58±6.44	10.472	0.001	93.62±1.01	97.23±0.59	6.874	0.000
观察组	50	75.05±15.90	97.14±5.91	15.461	0.000	93.47±0.92	99.23±0.68	8.622	0.000
t值	?	0.697	14.762	?	?	0.196	7.859	?	?
P值	?	0.572	0.000	?	?	0.816	0.000	?	?

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