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中华神经创伤外科电子杂志 ›› 2023, Vol. 09 ›› Issue (02) : 102 -107. doi: 10.3877/cma.j.issn.2095-9141.2023.02.007

临床研究

重复经颅磁刺激联合分级运动想象训练对脑梗死后偏瘫患者运动功能及神经功能的影响
黄志毅(), 赵娟   
  1. 350000 福州,解放军联勤保障部队第九〇〇医院康复医学科
  • 收稿日期:2022-09-26 出版日期:2023-04-15
  • 通信作者: 黄志毅

Effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction

Zhiyi Huang(), Juan Zhao   

  1. Department of Rehabilitation Medicine, the 900th Hospital of the PLA Joint Support Force, Fuzhou 350000, China
  • Received:2022-09-26 Published:2023-04-15
  • Corresponding author: Zhiyi Huang
引用本文:

黄志毅, 赵娟. 重复经颅磁刺激联合分级运动想象训练对脑梗死后偏瘫患者运动功能及神经功能的影响[J]. 中华神经创伤外科电子杂志, 2023, 09(02): 102-107.

Zhiyi Huang, Juan Zhao. Effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(02): 102-107.

目的

探讨重复经颅磁刺激联合分级运动想象训练对脑梗死后偏瘫患者运动功能及神经功能的影响。

方法

前瞻性纳入2018年5月至2020年9月解放军联勤保障部队第九〇〇医院康复医学科收治的脑梗死后偏瘫患者96例,采用随机数字表法分为对照组和观察组,每组48例。对照组患者给予重复经颅磁刺激,观察组患者给予重复经颅磁刺激联合分级运动想象训练,2组患者均进行4周的治疗。观察2组患者治疗前后的巴氏指数(BI)、Fugl-Meyer运动功能量表(FMA)评分、美国国立卫生研究院卒中量表(NIHSS)评分、血清一氧化氮(NO)、内皮素-1(ET-1)等水平变化。

结果

2组患者治疗后的BI指数、FMA评分较治疗前升高,且观察组患者的BI指数、FMA评分高于对照组,差异有统计学意义(P<0.05)。2组患者治疗后的NIHSS评分较治疗前降低,且观察组低于对照组,差异有统计学意义(P<0.05)。2组患者治疗后的NO水平较治疗前升高,ET-1水平较治疗前降低,且试验组患者的NO水平高于对照组,ET-1水平皆低于对照组,差异均具有统计学意义(P<0.05)。

结论

重复经颅磁刺激联合分级运动想象训练治疗脑梗死后偏瘫患者的疗效确切,能够提升患者的日常生活能力和运动功能,促进患者神经功能的恢复和保护血管内皮功能,值得借鉴及推广。

Objective

To explore the effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction.

Methods

Ninety-six patients with hemiplegia after cerebral infarction who were prospectively admitted to Rehabilitation Medicine Department of the 900th Hospital of the PLA Joint Support Force from May 2018 to September 2020, were divided into control group and observation group, with 48 patients in each group. The patients in the control group were given repetitive transcranial magnetic stimulation, and the patients in the observer group were given repetitive transcranial magnetic stimulation combined with graded motor imagination training. The patients in both groups were treated for 4 weeks. The changes of Barthel index (BI), Fugl Meyer motor function scale (FMA) scores, National Institute of Health stroke scale (NIHSS) scores, serum nitric oxide (NO), endothelin-1 (ET-1) levels were observed before and after treatment.

Results

After treatment, The BI and FMA score of the two groups were higher than those before treatment, and the BI and FMA score of the observation group were higher than those of the control group (P<0.05). After treatment, the NIHSS score of the two groups was lower than before treatment, and the observation group was lower than the control group (P<0.05). After treatment, the level of NO in the two groups was higher than that before treatment, and the level of ET-1 was lower than that before treatment, and the level of NO in the observation group was higher than that in the control group, and the level of ET-1 was lower than that in the control group (P<0.05).

Conclusion

Repetitive transcranial magnetic stimulation combined with graded motor imagery training is effective in treating hemiplegia patients after cerebral infarction. It can improve the activity of daily living and motor function of patients, promote the recovery of patients' neurological function and protect vascular endothelial function, which is worthy of reference and promotion.

表1 2组患者的一般资料比较
Tab.1 Comparison of general data of two groups
表2 2组患者的BI、FMA评分比较(分,±s
Tab.2 Comparison of BI and FMA score between two groups (score, Mean±SD)
表3 2组患者的NIHSS评分比较(分,±s
Tab.3 Comparison of NIHSS score between two groups (score, Mean±SD)
表4 2组患者的血清NO、ET-1水平比较(±s
Tab.4 Comparison of serum NO and ET-1 levels between two groups (Mean±SD)
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