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中华神经创伤外科电子杂志 ›› 2018, Vol. 04 ›› Issue (04) : 201 -204. doi: 10.3877/cma.j.issn.2095-9141.2018.04.003

所属专题: 文献

临床研究

探讨振幅整合脑电图对高分级动脉瘤性蛛网膜下腔出血患者预后的预测作用
严衍庆1, 蔡嘉伟1, 方文华1, 康德智1,()   
  1. 1. 350005 福州,福建医科大学附属第一医院神经外科
  • 收稿日期:2018-06-06 出版日期:2018-08-15
  • 通信作者: 康德智
  • 基金资助:
    福建省科技厅重大专项(2014YZ0003-1)

Investigating the predictive effect of amplitude integrated electroencephalography on prognosis of patients with high grade aneurysmal subarachnoid hemorrhage

Yanqing Yan1, Jiawei Cai1, Wenhua Fang1, Dezhi Kang1,()   

  1. 1. Department of Neurosurgery, First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China
  • Received:2018-06-06 Published:2018-08-15
  • Corresponding author: Dezhi Kang
  • About author:
    Corresponding author: Kang Dezhi, Email:
引用本文:

严衍庆, 蔡嘉伟, 方文华, 康德智. 探讨振幅整合脑电图对高分级动脉瘤性蛛网膜下腔出血患者预后的预测作用[J]. 中华神经创伤外科电子杂志, 2018, 04(04): 201-204.

Yanqing Yan, Jiawei Cai, Wenhua Fang, Dezhi Kang. Investigating the predictive effect of amplitude integrated electroencephalography on prognosis of patients with high grade aneurysmal subarachnoid hemorrhage[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2018, 04(04): 201-204.

目的

探讨振幅整合脑电图(aEEG)对预测高分级动脉瘤性蛛网膜下腔出血(aSAH)患者预后的临床价值。

方法

前瞻性收集2016年12月至2018年2月就诊于福建医科大学附属第一医院神经外科的23例高分级aSAH患者的临床资料。术后监测患者的aEEG,将所得出的aEEG分为aEEG正常振幅组与aEEG异常振幅组,并根据患者出院后3个月随访的改良Rankin量表(mRS)评分评价患者预后情况,将2组的预后进行统计分析。

结果

23例患者中,aEEG正常振幅组6例,均预后良好;aEEG异常振幅组17例,其中预后良好3例,预后不良14例。异常振幅组患者中9例为非持续正常状态,5例低电压状态,3例水平趋势状态,3例水平趋势状态的患者均死亡。aEEG出现异常者预后比正常者差,差异具有统计学意义(P=0.001)。

结论

高分级aSAH术后aEEG监测振幅异常可作为判断预后不良的预测指标,aEEG呈水平趋势改变提示严重不良预后。

Objective

To investigate the clinical value of amplitude-integrated electroencephalography in predicting the prognosis of patients with high grade aneurysmal subarachnoid hemorrhage.

Methods

Prospectively collected amplitude-enhanced EEG and clinical data of 23 patients with high-grade aSAH who underwent neurosurgery from the First Affiliated Hospital of Fujian Medical University from December 2016 to February 2018. The obtained aEEG was divided into aEEG normal group and aEEG abnormal group, and the prognosis of patients was evaluated according to the modified Rankin scale (mRS) scores of patients who were followed up for 3 months after discharge. The aEEG classification and prognosis were statistically analyzed.

Results

Of the 23 patients, 6 patients in the aEEG normal amplitude group had a good prognosis; 17 patients with aEEG abnormal amplitude group, including 3 patients with good prognosis and 14 patients with poor prognosis. Abnormal amplitude was 17 cases (9 of which were non-sustained normal amplitude group, 5 low voltage group, and 3 horizontal trend group). Three patients in the horizontal trend group died. The prognosis of aEEG was worse than normal, and the difference was statistically significant (P=0.001).

Conclusion

AEEG monitoring of abnormal amplitude after high-grade aSAH surgery can be used as a predictor of poor prognosis, amplitude integrated electroencephalogram showed a horizontal trend changes suggest a serious adverse prognosis.

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