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中华神经创伤外科电子杂志 ›› 2015, Vol. 01 ›› Issue (03) : 169 -172. doi: 10.3877/cma.j.issn.2095-9141.2015.03.011

专题笔谈

神经干细胞与创伤性颅脑损伤后的神经修复
高亮1,(), 章小清1   
  1. 1.200000 上海,同济大学附属第十人民医院神经外科
  • 收稿日期:2014-12-13 出版日期:2015-06-15
  • 通信作者: 高亮
  • 基金资助:
    国家基础研究计划资助(2012CB966300)国家重大科学研究计划资助(2012CB966300)

Neural stem cells and nerve repair after craniocerebral injury

Liang Gao1,(), Xiaoqing Zhang1   

  1. 1.Department of Neurosurgery,Tenth People's Hospital of Tongji University,Shanghai 200000,China
  • Received:2014-12-13 Published:2015-06-15
  • Corresponding author: Liang Gao
引用本文:

高亮, 章小清. 神经干细胞与创伤性颅脑损伤后的神经修复[J]. 中华神经创伤外科电子杂志, 2015, 01(03): 169-172.

Liang Gao, Xiaoqing Zhang. Neural stem cells and nerve repair after craniocerebral injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2015, 01(03): 169-172.

外伤性脑损伤是当今社会致死、致残的主要原因。神经干细胞(NSCs)的治疗研究就是试图通过引入新的细胞来替代丧失的神经元,或者所引进细胞通过神经营养作用来增加受损的神经细胞的存活、可塑性和功能的恢复来发挥作用。本文从干细胞在神经修复治疗中的背景、机制、策略及展望几个方面进行了综述。

Craniocerebral injury is the leading cause of lethal and disability in nowadays.Treatment of neural stem cells (NSCs) is trying to introduce new cells to replace dead neurons, or increase the survival, plasticity and functional recovery of the damaged nerve cells by neurotrophic effects on the introduced nerve cells. This article has reviewed from aspects as background,machanisms,strategies and prospects on stem cells nerve repair therapy.

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