Progress in the application of alginate saline gel scaffolds in the repair of skull defects

doi:10.3877/cma.j.issn.2095-9141.2024.05.009

Abstract

Abstract:

Alginate gel has good histocompatibility and biodegradability， and has been widely studied and applied in bone tissue repair as a three-dimensional culture scaffold，and remarkable progress has been made. Because of its superior mechanical properties and biological activities， alginate gel can play a continuous role in the skull defect area， so as to promote the regeneration， proliferation and differentiation of bone cells， accelerate the process of bone tissue repair， and improve its therapeutic effect in bone tissue repair.This review focuses on the application of alginate saline gel combined with 3D stent in the repair of skull defects in recent years， in order to provide a reference for its clinical application.

Key words: Skull defect repair, Alginate, Hydrogel scaffold, Histocompatibility

Mingce Sun, Shihuan Han. Progress in the application of alginate saline gel scaffolds in the repair of skull defects[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2024, 10(05): 310-314.

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