To compare and analyze the effectiveness of mobile stroke unit (MSU) and conventional treatment mode of acute ischemic stroke (AIS).

Sixty patients with AIS were selected from Encephalopathy Department of Nanshi Hospital Affiliated to Henan University from October 2019 to January 2020. The patients were randomly divided into MSU group (30 cases) and routine group (30 cases). In the MSU group, MSU equipped with 16-slice mobile CT was used to evaluate the neurological function, brain mobile CT scanning diagnosis and recombinant tissue-type plasminogen activator alteplase (rt-PA) intravenous thrombolysis for AIS. The patients in the routine group under routine treatment mode were initially treatment by first aid on site and transported to the hospital by 120 ambulance. The neurological assessment, brain CT scanning were performed in the Emergency Department. The diagnosis was determined in stroke experts. Then the patients were admitted to the stroke center for rt-PA intravenous thrombolysis. The initial contact time, CT scan time, rt-PA thrombolytic time, and the degree of neurological deficit before and after thrombolytic therapy were compared and analyzed between the two groups.

The total effective rate of MSU group was higher than that of routine group, the difference were statistically significant (P<0.05). The time from the first medical contact to the completion of head CT examination in MSU group was significantly less than that in routine group (the average time was shortened by 28.72 min), and the time from the first medical contact to the start of intravenous thrombolysis was significantly less than that in routine group (the average time was shortened by 34.81 min). The difference between the two groups was statistically significant (P<0.05). The change of NIHSS score in MSU group was better than that in routine group (P<0.05).

The use of MSU mode for AIS can significantly shorten the time of brain CT scanning and rt-PA intravenous thrombolysis for the treatment of rt-PA intravenous thrombolysis, which resulted in significant improvement of neurological function and clinical efficacy of AIS patients.