To discuss the effect and the mechanism of minimally invasive intracranial hematoma drainage on hypertensive cerebral hemorrhage in the aged people.

One hundred and sixteen cases of aged patients with hypertensive cerebral hemorrhage, all are supratentorial hematomas with volume less than 35 ml, were selected in this study. The patients’ relatives were given detail information of advantages and disadvantages of the two different treatment methods. According to their opinion, patients were divided into two groups, the research group and the control group, each group has fifty eight patients. There is no significant different in the age, gender, the location and the volume of hematoma, the onset of hemiplegia, and the GCS between the two groups. Patients in research group underwent minimally invasive intracranial hematoma drainage, while patients in control group underwent conservative treatment. The changes of serum tumor necrosis factor-α(TNF-α), interleukin-6(IL-6),hematoma volume, surrounding edema, and national institutes of health stroke scale(NIHSS) of the two groups were observed and compared.

Before treatment, the IL-6 of the two groups were (11.3±2.8) ng/L and (11.8±3.2) ng/L respectively, the TNF-α were (42.8±5.3) μg/L and (43.2±4.6) μg/L respectively. There were no significant difference between the two group(P>0.05). After treatment, the IL-6 (15.4±3.2) ng/L and the TNF-α(44.2±4.3) μg/L level of research group were significantly lower than that of control group (28.2±4.2) ng/L and (50.6±4.8) μg/L (P<0.05). Before treatment, the hematoma volume of the two group were (11.3±2.8) ml and (11.8±3.2) ml respectively, the surrounding edema volume were (10.2±4.8) ml and (10.3±5.2) ml respectively. There were no significant difference between the two group(P>0.05). After treatment, the hematoma volume (8.8±4.8) ml and the edema volume (6.2±3.6) ml of research group were significantly lower than that of control group (18.6±5.3) ml and (18.8±7.2) ml (P<0.05). Before treatment, the NIHSS of the two groups were (12.8±4.2) and (12.6±4.3) respectively, compared with no significant difference (P<0.05). After treatment, the NIHSS of research group (4.6±2.2) were significantly lower than that of control group (6.8±1.1) (P<0.05).

Minimally invasive intracranial hematoma drainage can rapidly reduce the mass effect of the hematoma, lower the intracranial pressure, alleviate cerebral edema via reduce inflammatory reaction of brain tissue, improve the function of central nervous system, thus it can improve the curative effect of hypertensive cerebral hemorrhage in the aged people.