Effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction

doi:10.3877/cma.j.issn.2095-9141.2023.02.007

Abstract

Abstract:

Objective

To explore the effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction.

Methods

Ninety-six patients with hemiplegia after cerebral infarction who were prospectively admitted to Rehabilitation Medicine Department of the 900^th Hospital of the PLA Joint Support Force from May 2018 to September 2020, were divided into control group and observation group, with 48 patients in each group. The patients in the control group were given repetitive transcranial magnetic stimulation, and the patients in the observer group were given repetitive transcranial magnetic stimulation combined with graded motor imagination training. The patients in both groups were treated for 4 weeks. The changes of Barthel index (BI), Fugl Meyer motor function scale (FMA) scores, National Institute of Health stroke scale (NIHSS) scores, serum nitric oxide (NO), endothelin-1 (ET-1) levels were observed before and after treatment.

Results

After treatment, The BI and FMA score of the two groups were higher than those before treatment, and the BI and FMA score of the observation group were higher than those of the control group (P<0.05). After treatment, the NIHSS score of the two groups was lower than before treatment, and the observation group was lower than the control group (P<0.05). After treatment, the level of NO in the two groups was higher than that before treatment, and the level of ET-1 was lower than that before treatment, and the level of NO in the observation group was higher than that in the control group, and the level of ET-1 was lower than that in the control group (P<0.05).

Conclusion

Repetitive transcranial magnetic stimulation combined with graded motor imagery training is effective in treating hemiplegia patients after cerebral infarction. It can improve the activity of daily living and motor function of patients, promote the recovery of patients' neurological function and protect vascular endothelial function, which is worthy of reference and promotion.

Key words: Repetitive transcranial magnetic stimulation, Graded motor imagery training, Hemiplegia after cerebral infarction, Motor function, Neurological function

Zhiyi Huang, Juan Zhao. Effects of repetitive transcranial magnetic stimulation combined with graded motor imagery training on motor function and neurological function in patients with hemiplegia after cerebral infarction[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(02): 102-107.

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References 20

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组别	例数	年龄（岁，±s）	性别（男/女）	体质量指数（kg/m²，±s）	病程（d，±s）	偏瘫侧（左侧/右侧）	单侧肢体瘫痪时间（d，±s）	脑梗死影像分级（±s）
对照组	48	57.84±7.73	21/27	21.86±2.34	27.49±5.17	26/22	12.15±2.29	1.85±0.36
观察组	48	58.62±8.15	23/25	21.73±2.21	27.61±5.38	24/24	11.85±2.16	1.83±0.33
χ²/t值		0.481	0.168	0.280	0.111	0.167	0.660	0.284
P值		0.632	0.682	0.780	0.912	0.683	0.511	0.777

组别	例数	年龄（岁，±s）	性别（男/女）	体质量指数（kg/m²，±s）	病程（d，±s）	偏瘫侧（左侧/右侧）	单侧肢体瘫痪时间（d，±s）	脑梗死影像分级（±s）
对照组	48	57.84±7.73	21/27	21.86±2.34	27.49±5.17	26/22	12.15±2.29	1.85±0.36
观察组	48	58.62±8.15	23/25	21.73±2.21	27.61±5.38	24/24	11.85±2.16	1.83±0.33
χ²/t值		0.481	0.168	0.280	0.111	0.167	0.660	0.284
P值		0.632	0.682	0.780	0.912	0.683	0.511	0.777

组别	例数	BI评分				FMA评分
组别	例数	治疗前	治疗后	t值	P值	治疗前	治疗后	t值	P值
对照组	48	34.28±5.16	76.45±6.82	34.163	<0.001	45.87±5.06	73.58±7.73	20.780	<0.001
观察组	48	34.39±5.21	88.37±7.19	42.119	<0.001	45.71±4.96	82.64±8.15	26.818	<0.001
t值		0.104	8.333			0.156	5.588
P值		0.917	<0.001			0.876	<0.001

组别	例数	BI评分				FMA评分
组别	例数	治疗前	治疗后	t值	P值	治疗前	治疗后	t值	P值
对照组	48	34.28±5.16	76.45±6.82	34.163	<0.001	45.87±5.06	73.58±7.73	20.780	<0.001
观察组	48	34.39±5.21	88.37±7.19	42.119	<0.001	45.71±4.96	82.64±8.15	26.818	<0.001
t值		0.104	8.333			0.156	5.588
P值		0.917	<0.001			0.876	<0.001

组别	例数	治疗前	治疗后	t值	P值
对照组	48	18.39±3.62	8.32±2.16	16.550	<0.001
观察组	48	18.51±3.71	5.74±1.38	22.351	<0.001
t值		0.160	6.974
P值		0.873	<0.001

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