To explore the clinical application of diffusion tensor imaging (DTI) to reconstruct the conductive beam to guide the resection of high-grade glioma (HGG).

The clinical data of HGG patients who underwent surgery in the same medical group from August 2018 to October 2020 in the Neurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively. They were divided into DTI group and non-DTI group according to whether DTI examination was performed before surgery. DTI group used DTI reconstruction guided beam + traditional enhanced NMR to guide surgical resection; the non-DTI group used traditional enhanced NMR to guide surgical resection. The gender, age, tumor location, tumor grade, degree of resection, Karnofsky performance status (KPS) scores before surgery and discharge, postoperative hospital stay, and postoperative complications were collected and compared in the two groups of patients.

According to the inclusion and exclusion criteria, a total of 40 patients were included, including 15 cases in DTI group and 25 cases in non-DTI group. The incidence of postoperative neurological complications in DTI group was lower than that in non-DTI group. The number of hospitalization days was less than that of the non-DTI group (P<0.05). There was no significant difference in the degree of resection, general surgical complications and postoperative KPS score between the two groups (P>0.05). The postoperative KPS score in DTI group was higher than that before operation, and the postoperative function recovered compared with that before operation (P<0.05).

The application of DTI conductive beam reconstruction technology to guide surgical resection in HGG patients can maximize the resection of the tumor under the premise of protective function, improve the prognosis of the patient, reduce the postoperative disability rate, and improve the quality of life of the patient.