Effect of repetitive transcranial magnetic stimulation on nerve regulation in acute cervical spinal cord injury

doi:10.3877/cma.j.issn.2095-9141.2021.01.008

Abstract

Abstract:

Objective

To investigate the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS) in patients with acute cervical spinal cord injury.

Methods

Three hundred and twenty patients with grade American Spinal Cord Injury Association (ASIA) A-D cervical spinal cord injury were divided into control group (n=215) and treatment group (n=105) according to the admission department. The control group received routine treatment and rehabilitation treatment, while the treatment group was treated with rTMS on the basis of routine treatment. The ASIA motor score, application time of suction machine, catheter use time, paralytic intestinal obstruction time, mortality and 30 d pneumonia cure rate of the two groups before and after treatment were compared.

Results

Before treatment, there was no significant difference in gender, age, ASIA motor score and injury site between the two groups (P>0.05). After 30 d of treatment, the ASIA motor score of the treatment group was higher than that of the control group (P<0.05). The time of wearing respiratory muscle, indwelling catheter and paralytic intestinal obstruction in the treatment group were significantly shorter than those in the control group (P<0.05); the incidence of pneumonia in the treatment group was significantly lower than that in the control group, and the 30 d cure rate was significantly higher than that in the control group (P<0.05).

Conclusion

rTMS combined with traditional therapy can significantly improve the movement, lung function, defecation and urine function of patients with acute cervical spinal cord injury, the effect is better than traditional therapy.

Key words: Acute cervical spinal cord injury, Repeated transcranial magnetic stimulation, Pulmonary infection, Defecation dysfunction

Dongsheng Zhao, Xiaohua Bie, Huimin Hu, Jungang Xue, Guohua Deng, Wenyuan Wei, Ying Dang. Effect of repetitive transcranial magnetic stimulation on nerve regulation in acute cervical spinal cord injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2021, 07(01): 33-36.

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References 25

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组别	例数	性别（男/女）	年龄（岁，±s）	ASIA评分（分，±s）	损伤部位[例(%)]
组别	例数	性别（男/女）	年龄（岁，±s）	ASIA评分（分，±s）	C2～C4	C5～C7
治疗组	105	86/19	54.72±20.23	2.23±0.86	47(44.8)	58(55.2)
对照组	215	177/38	52.89±18.53	2.13±1.07	95(44.2)	120(55.8)
t/χ²值		0.009	0.028	0.398	0.010
P值		0.927	0.779	0.692	0.922

组别	例数	性别（男/女）	年龄（岁，±s）	ASIA评分（分，±s）	损伤部位[例(%)]
组别	例数	性别（男/女）	年龄（岁，±s）	ASIA评分（分，±s）	C2～C4	C5～C7
治疗组	105	86/19	54.72±20.23	2.23±0.86	47(44.8)	58(55.2)
对照组	215	177/38	52.89±18.53	2.13±1.07	95(44.2)	120(55.8)
t/χ²值		0.009	0.028	0.398	0.010
P值		0.927	0.779	0.692	0.922

组别	例数	男/女	ASIA评分（分，±s）	呼吸机使用时间（d，±s）	尿管使用时间（d，±s）	麻痹性肠梗阻时间（d，±s）	30 d病死率[例(%)]
治疗组	105	86/19	3.83±0.75	6.28±3.92	9.34±1.88	4.03±1.49	1(0.95)
对照组	215	177/38	2.67±1.06	9.60±6.12	15.78±5.58	7.74±3.87	5(2.33)
t/χ²值			4.924	2.892	7.004	4.740	0.169
P值			0.000	0.005	0.000	0.000	0.681

组别	例数	男/女	ASIA评分（分，±s）	呼吸机使用时间（d，±s）	尿管使用时间（d，±s）	麻痹性肠梗阻时间（d，±s）	30 d病死率[例(%)]
治疗组	105	86/19	3.83±0.75	6.28±3.92	9.34±1.88	4.03±1.49	1(0.95)
对照组	215	177/38	2.67±1.06	9.60±6.12	15.78±5.58	7.74±3.87	5(2.33)
t/χ²值			4.924	2.892	7.004	4.740	0.169
P值			0.000	0.005	0.000	0.000	0.681

组别	例数	肺炎发病率	30 d治愈率
治疗组	105	60(57.14)	52(86.67)
对照组	215	205(87.91)	123(60.00)
χ²值		72.349	14.717
P值		0.000	0.0001

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