Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Neurotraumatic Surgery(Electronic Edition) ›› 2021, Vol. 07 ›› Issue (01): 6-11. doi: 10.3877/cma.j.issn.2095-9141.2021.01.002

Special Issue:

• Traumatic Brain Injurys • Previous Articles     Next Articles

Relationship between Beagle’s intracranial pressure and external pressure after explosion

Gang Cheng1, Yanteng Li1, Boyuan Wei1, Shuwei Wang1, Shuai Liu1, Bangxin Liu2, Yanan Liu1, Jianning Zhang1,()   

  1. 1. Department of Neurosurgery, The First Medical Center, General Hospital of PLA, Beijing 100048, China
    2. Department of Neurosurgery, General Hospital of Central Theater Command, Wuhan 430070, China
  • Received:2020-12-29 Online:2021-02-15 Published:2021-02-15
  • Contact: Jianning Zhang

Abstract:

Objective

To investigate the changes of Beagle’s intracrannial pressure after explosion and explore the features of shock wave in the cranium.

Methods

Forty-six healthy adult Beagle dogs were used in the experiment. The explosion was carried out in free field, in the cabin and under the water. The explosion source was 0.65, 1.00 and 3.50 kg column-shaped tri-nitro-toluene. In free field and cabin explosion, Beagle dogs were anaesthesized and fixed in supine position with the head toward the explosion source. In under-water explosion, the dogs were fixed in life buoy with head above the water. The external shock wave pressure, intracranial shock wave pressure from cranium and brain tissue were measured. Neurological scores for big animals were used to assess trauma severity of the animal at different time points.

Results

In free field and cabin experiment, the shock wave can penetrate the cranium and enter the brain. After passing through the cranium, the shock wave only shows a decrease in amplitude, and the wave form was similar as that of the field. In free field explosion, there was exponent relationship of the peak value of the wave between those in the field and those passing through the cranium (R2=0.804). In free field and under-water experiment, the wave form of that coming from the brain tissue was similar as that of the field, which means that shock wave can entering brain tissue from chest and abdomen. In under-water explosion, there was exponent relationship of the peak value of the wave between those in the field and those coming through the cranium (R2=0.767). In cabin explosion, the wave form was very complex because of the complicated influence factors. No clear relationship of peak wave was discovered between those in the field and in the cranium. There was the most serious severity of the animal in under-water group and the lightest in free field.

Conclusion

In different explosion field, shock wave can enter into cranium either by passing through the cranium or entering brain tissue from chest and abdomen. The wave form was affected by many factors.

Key words: Intracranial pressure, Free field, Cabin, Under-water, Shock wave, Cranium, Brain tissue

京ICP 备07035254号-20
Copyright © Chinese Journal of Neurotraumatic Surgery(Electronic Edition), All Rights Reserved.
Tel: 010-64229160 E-mail: zhsjcswk2015@163.com
Powered by Beijing Magtech Co. Ltd