To observe the effect of transcranial direct current stimulation (tDCS) combined with continuous theta-burst stimulation (cTBS) on dual-mode speech stimuli for non-fluent aphasia after stroke.

Sixty-four patients with non-fluent aphasia admitted to Rehabilitation Medicine Department of the Third People’s Hospital of Mianyang City from January 2017 to June 2019 were divided into a treatment group of 32 cases and a control group of 32 cases by random number table. Both groups used conventional speech rehabilitation training, the treatment group added tDCS combined with cTBS stimulation, and the control group used false stimulation. Which the site, treatment mode, and treatment time were the same as the treatment group. Both treatment were once a day, 6 times a week, for 5 consecutive weeks, the Chinese version of the Western Aphasia Set and functional independence scale were used to evaluate before and after the course of treatment. The changes of aphasia quotient (AQ), performance quotient (PQ), cerebral cortex quotient (CQ) and functional independence score were observed before and after treatment.

After treatment, AQ, PQ and CQ scores of the two groups were significantly better than those before treatment (P<0.05). The two groups of treatments were effective, but the comparison between the two groups after treatment showed that the efficacy of AQ and CQ was better than the control group (P<0.05), there was no significant difference in PQ scores between the two groups (P>0.05). After treatment, the functional independence scores of the two groups were higher than before, the difference was statistically significant (P<0.05), but there was no significant difference in the degree of improvement between the two groups (P>0.05).

The combination of tDCS and cTBS to stimulate language bimodal pathway can significantly improve the language function of patients with non-fluent aphasia after stroke.