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中华神经创伤外科电子杂志 ›› 2017, Vol. 03 ›› Issue (01) : 44 -47. doi: 10.3877/cma.j.issn.2095-9141.2017.01.011

所属专题: 文献

综述

依达拉奉给药途径及治疗急性脑梗死的研究进展
张岩1, 张丽1, 徐如祥1,()   
  1. 1. 100700 北京,陆军总医院附属八一脑科医院
  • 收稿日期:2016-11-28 出版日期:2017-02-15
  • 通信作者: 徐如祥

Research progress of edaravone administration in treatment of acute cerebral infarction

Yan Zhang1, Li Zhang1, Ruxiang Xu1,()   

  1. 1. The Affiliated Bayi Brain Hospital, The PLA Army General Hospital, Beijing 100700, China
  • Received:2016-11-28 Published:2017-02-15
  • Corresponding author: Ruxiang Xu
  • About author:
    Corresponding author: Xu Ruxiang, Email:
引用本文:

张岩, 张丽, 徐如祥. 依达拉奉给药途径及治疗急性脑梗死的研究进展[J]. 中华神经创伤外科电子杂志, 2017, 03(01): 44-47.

Yan Zhang, Li Zhang, Ruxiang Xu. Research progress of edaravone administration in treatment of acute cerebral infarction[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2017, 03(01): 44-47.

依达拉奉是治疗急性脑梗死的常用药,可清除自由基、抑制脂质过氧化、延迟神经细胞死亡,从而减轻脑水肿和脑组织损伤。依达拉奉对急性脑梗死等多种疾病均有疗效。不同的给药途径决定了依达拉奉到达病变部位的时间、血药浓度和药效持续时间等参数,可直接影响依达拉奉的药效。因此,本文对依达拉奉的临床应用和给药途径进行了综述。

Edaravone is one of common medinces treating acute cerebral infarction, which can scavenge free radicals, can inhibit lipid peroxidation and can delay neuronal cell death, then reducs cerebral edema and brain tissue damage. Edaravone can be applied to treat acute cerebral infarction and other diseases. Different routes of administration of edaravone determine therapeutic parameters, the time to reach injured parts, plasma concentration and pharmacodynamic parameters. Administration routes can directly affect the efficacy of Edaravone. Therefore, this article reviewed edaravone clinical application and route of administration.

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