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中华神经创伤外科电子杂志 ›› 2015, Vol. 01 ›› Issue (05) : 41 -45. doi: 10.3877/cma.j.issn.2095-9141.2015.05.011

所属专题: 文献

专题笔谈

脑肿瘤干细胞的发育相关信号通路
郭阳1, 徐如祥2,()   
  1. 1. 510282 广州,南方医科大学珠江医院神经外科
    2. 100700 北京,北京军区神经外科研究所
  • 收稿日期:2015-03-11 出版日期:2015-10-15
  • 通信作者: 徐如祥
  • 基金资助:
    广东省药学会基金(2011X19); 国家自然科学基金(30801184); 广东省科技计划重点专项(2011A030400007)

The development of brain tumor stem cells relevant signaling pathway

Yang Guo1, Ruxiang Xu2,()   

  1. 1. Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China
    2. Institute of Neuroscience of Beijing Military Region, Beijing 100700, China
  • Received:2015-03-11 Published:2015-10-15
  • Corresponding author: Ruxiang Xu
  • About author:
    Corresponding author: Xu Ruxiang, Email:
引用本文:

郭阳, 徐如祥. 脑肿瘤干细胞的发育相关信号通路[J]. 中华神经创伤外科电子杂志, 2015, 01(05): 41-45.

Yang Guo, Ruxiang Xu. The development of brain tumor stem cells relevant signaling pathway[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2015, 01(05): 41-45.

脑胶质瘤干细胞存在于微环境中,微环境中包含有多种的细胞信号调控分子,胶质瘤的生物学行为正是由细胞外微环境作用于细胞内信号所决定的。脑胶质瘤干细胞信号通路的研究已成为脑胶质瘤研究的热点。本文将重点综述脑胶质瘤干细胞中几条重要的与神经干细胞相关的信号通路,为更全面的认识脑胶质瘤细胞信号、以及开拓新的脑胶质瘤治疗方法提供基础证据。

Glioma stem cells exist in the micro environment, which contains a variety of cell signal transduction molecules, and biological behavior of glioma is regulated by extracellular microenvironment on the intracellular signal. Glioma stem cell signaling pathways study has become the hot topics in the study of glioma. This review focuses on several important in glioma stem cells related to neural stem cell signaling pathways, for a more comprehensive understanding of glioma cell signal, and provide basic evidence to explore new glioma treatment.

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