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中华神经创伤外科电子杂志 ›› 2026, Vol. 12 ›› Issue (01) : 45 -51. doi: 10.3877/cma.j.issn.2095-9141.2026.01.007

综述

多模态技术在儿童脑功能区肿瘤切除术中的应用进展
赵文龙, 刘冬, 达娜, 古力米热, 张经, 木拉地力, 吉文玉†()   
  1. 830054　乌鲁木齐，新疆医科大学第一附属医院小儿神经外科
  • 收稿日期:2024-12-24 出版日期:2026-02-15
  • 通信作者: 吉文玉

Application progress of multimodal technology in pediatric brain functional area tumor resection

Wenlong Zhao, Dong Liu, Dana, Gulimire, Jing Zhang, Muradili, Wenyu Ji†()   

  1. Department of Pediatric Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:2024-12-24 Published:2026-02-15
  • Corresponding author: Wenyu Ji
  • Supported by:
    Special Training Program for Scientific and Technological Talents of Ethnic Minorities in Xinjiang(2022D03013)
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引用本文：

赵文龙, 刘冬, 达娜, 古力米热, 张经, 木拉地力, 吉文玉. 多模态技术在儿童脑功能区肿瘤切除术中的应用进展[J/OL]. 中华神经创伤外科电子杂志, 2026, 12(01): 45-51.

Wenlong Zhao, Dong Liu, Dana, Gulimire, Jing Zhang, Muradili, Wenyu Ji. Application progress of multimodal technology in pediatric brain functional area tumor resection[J/OL]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2026, 12(01): 45-51.

儿童脑肿瘤的发病率位居儿童恶性肿瘤第2位，且呈逐年上升趋势。尽管近年来临床治疗手段取得了显著进步，但患儿生存率改善仍有限。多模态技术可联合应用神经影像、术中导航及功能监测技术等多种手段，通过互补优势实现精准定位、功能保护及实时监测。随着相关技术的进步及神经肿瘤学新证据的积累，多模态技术已广泛应用于成人神经外科。然而，儿童脑发育的特殊性及与成人的高度异质性，导致该技术在儿科领域的应用面临独特挑战。本文系统综述多模态技术在儿童脑功能区肿瘤的应用进展，围绕术前多模态影像学的高精度重建、术中无创与实时解剖修正技术的针对性应用、术中神经电生理及唤醒麻醉的适配改良，以及多模态技术闭环整合策略的构建等方面展开讨论，旨在为优化手术策略提供参考。

关键词: 多模态技术, 脑肿瘤, 脑功能区, 儿童

Pediatric brain tumors rank the second in the incidence of childhood malignant tumors with an increasing trend year by year. Despite significant advances in clinical treatments in recent years, improvement in survival rates for children remains limited. Multimodal technology can be combined with various techniques such as neuroimaging, intraoperative navigation, and functional monitoring to achieve precise positioning, functional protection, and real-time monitoring through complementary advantages. With the advancement of related technologies and the accumulation of new evidence in Nneurooncology, this technology has been widely applied in adult Neurosurgery. However, the particularity of child brain development and its high heterogeneity with adults pose unique challenges for the application of this technology in the field of pediatrics. This review focuses on the application progress of multimodal technologies in the treatment of pediatric brain tumors in functional areas, and systematically elaborates on the core aspects including high-precision reconstruction of preoperative multimodal imaging, targeted application of intraoperative non-invasive and real-time anatomical correction technologies, adaptive improvement of intraoperative neuroelectrophysiological monitoring and awake anesthesia, as well as the construction of a closed-loop integration strategy for multimodal technologies, so as to provide references for optimizing surgical strategies.

Key words: Multimodal technology, Brain tumor, Brain functional areas, Pediatric
图1 儿童功能区脑肿瘤多模态技术联合应用流程
Fig.1 Multimodal technology integration workflow for pediatric brain tumor resection
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[15] 柯嘉慧, 刘新献. 双侧岩下窦静脉采血精准诊断儿童疑难库欣病1例并文献复习[J/OL]. 中华介入放射学电子杂志, 2026, 14(01): 114-117.
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