切换至 "中华医学电子期刊资源库"

中华神经创伤外科电子杂志 ›› 2024, Vol. 10 ›› Issue (02) : 117 -121. doi: 10.3877/cma.j.issn.2095-9141.2024.02.010

综述

轻型创伤性脑损伤远期后遗症流行病学的研究进展
张薇1, 郭姗姗2,()   
  1. 1. 300309 天津,武警特色医学中心神经外科
    2. 100088 北京,火箭军特色医学中心全科医学科
  • 收稿日期:2023-06-05 出版日期:2024-04-15
  • 通信作者: 郭姗姗

Epidemiology study progress of forward sequela of mild traumatic brain injury

Wei Zhang1, Shanshan Guo2,()   

  1. 1. Department of Neurosurgery, Characteristic Medical Center of People's Armed Police Force, Tianjin 300309, China
    2. Department of General Practice, Characteristic Medical Center of PLA Rocket Force, Beijing 100088, China
  • Received:2023-06-05 Published:2024-04-15
  • Corresponding author: Shanshan Guo
引用本文:

张薇, 郭姗姗. 轻型创伤性脑损伤远期后遗症流行病学的研究进展[J]. 中华神经创伤外科电子杂志, 2024, 10(02): 117-121.

Wei Zhang, Shanshan Guo. Epidemiology study progress of forward sequela of mild traumatic brain injury[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2024, 10(02): 117-121.

轻型创伤性脑损伤(mTBI)发生率较高,多数患者几周内便可从症状中恢复,但部分患者伤后症状可能持续数月或数年,严重影响患者及其家庭的生活质量。导致患者预后不良的相关因素不仅包括损伤类型和损伤机制,还包括年龄、损伤前状态、共病状况、环境因素及修复能力等。本文针对mTBI远期后遗症流行病学的研究进展作一综述,以期为临床精确诊断及个体化治疗提供参考。

The incidence of mild traumatic brain injury (mTBI) is relatively high, and most patients can recover from symptoms within a few weeks, but some patients may last for several months or years after injury, which seriously affects the quality of life of patients and their families. The relevant factors that lead to poor prognosis of patients not only include the type of damage and the damage mechanism, but also include age, pre injury status, the condition of the common disease, environmental factors, and repair ability. This article provides a review of the research progress on the epidemiology of long-term sequelae of mTBI, in order to provide reference for accurate clinical diagnosis and individualized treatment.

[1]
Dewan MC, Rattani A, Gupta S, et al. Estimating the global incidence of traumatic brain injury[J]. J Neurosurg, 2018, 130(4): 1080-1097. DOI: 10.3171/2017.10.JNS17352.
[2]
邹隽风,黄贤键,吴楚伟,等.中国颅脑创伤流行病学中存在的部分问题探讨[J].中华神经创伤外科电子杂志, 2021, 7(1): 59-62. DOI: 10.3877/cma.j.issn.2095-9141.2021.01.014.
[3]
Haarbauer-Krupa J, Pugh MJ, Prager EM, et al. Epidemiology of chronic effects of traumatic brain injury[J]. J Neurotrauma, 2021, 38(23): 3235-3247. DOI: 10.1089/neu.2021.0062.
[4]
Lumba-Brown A, Yeates KO, Sarmiento K, et al. Diagnosis and management of mild traumatic brain injury in children: a systematic review[J]. JAMA Pediatr, 2018, 172(11): e182847. DOI: 10.1001/jamapediatrics.2018.2847.
[5]
McInnes K, Friesen CL, MacKenzie DE, et al. Mild traumatic brain injury (mTBI) and chronic cognitive impairment: a scoping review[J]. PLoS One, 2017, 12(4): e0174847. DOI: 10.1371/journal.pone.0174847.
[6]
Babcock L, Byczkowski T, Wade SL, et al. Predicting postconcussion syndrome after mild traumatic brain injury in children and adolescents who present to the emergency department[J]. JAMA Pediatr, 2013, 167(2): 156-161. DOI: 10.1001/jamapediatrics.2013.434.
[7]
Haarbauer-Krupa J, Taylor CA, Yue JK, et al. Screening for post-traumatic stress disorder in a civilian emergency department population with traumatic brain injury[J]. J Neurotrauma, 2017, 34(1): 50-58. DOI: 10.1089/neu.2015.4158.
[8]
Corrigan JD, Hammond FM. Traumatic brain injury as a chronic health condition[J]. Arch Phys Med Rehabil, 2013, 94(6): 1199-1201. DOI: 10.1016/j.apmr.2013.01.023.
[9]
Chendrasekhar A, Kuczabski B, Cohen D, et al. Delayed sequelae related to mild traumatic brain injury in children[J]. Glob Pediatr Health, 2020, 7: 2333794x20947988. DOI: 10.1177/2333794x20947988.
[10]
Schorr E, Wade SL, Taylor HG, et al. Parenting styles as a predictor of long-term psychosocial outcomes after traumatic brain injury (TBI) in early childhood[J]. Disabil Rehabil, 2020, 42(17): 2437-2443. DOI: 10.1080/09638288.2019.1602676.
[11]
Langlois JA, Rutland-Brown W, Thomas KE. The incidence of traumatic brain injury among children in the United States: differences by race[J]. J Head Trauma Rehabil, 2005, 20(3): 229-238. DOI: 10.1097/00001199-200505000-00006.
[12]
Brown JB, Kheng M, Carney NA, et al. Geographical disparity and traumatic brain injury in America: rural areas suffer poorer outcomes[J]. J Neurosci Rural Pract, 2019, 10(1): 10-15. DOI: 10.4103/jnrp.jnrp_310_18.
[13]
Sinnott AM, Kontos AP, Collins MW, et al. Concussion symptoms among athletes: preinjury factors predict postinjury factors[J]. J Head Trauma Rehabil, 2020, 35(4): E361-E371. DOI: 10.1097/htr.0000000000000562.
[14]
Zahniser E, Temkin NR, Machamer J, et al. The functional status examination in mild traumatic brain injury: a TRACK-TBI sub-study[J]. Arch Clin Neuropsychol, 2019, 34(7): 1165-1174. DOI: 10.1093/arclin/acy103.
[15]
Brotfain E, Gruenbaum SE, Boyko M, et al. Neuroprotection by estrogen and progesterone in traumatic brain injury and spinal cord injury[J]. Curr Neuropharmacol, 2016, 14(6): 641-653. DOI: 10.2174/1570159x14666160309123554.
[16]
Gardner RC, Byers AL, Barnes DE, et al. Mild TBI and risk of parkinson disease: a chronic effects of neurotrauma consortium study[J]. Neurology, 2018, 90(20): e1771-e1779. DOI: 10.1212/wnl.0000000000005522.
[17]
张慧艳,冀兵. CXCL12与创伤性颅脑损伤后神经细胞凋亡的相关性[J].中华神经创伤外科电子杂志, 2019, 5(3): 179-181. DOI: 10.3877/cma.j.issn.2095-9141.2019.03.012.
[18]
Taylor HG, Orchinik LJ, Minich N, et al. Symptoms of persistent behavior problems in children with mild traumatic brain injury[J]. J Head Trauma Rehabil, 2015, 30(5): 302-310. DOI: 10.1097/htr.0000000000000106.
[19]
Haarbauer-Krupa J, Lee AH, Bitsko RH, et al. Prevalence of parent-reported traumatic brain injury in children and associated health conditions[J]. JAMA Pediatr, 2018, 172(11): 1078-1086. DOI: 10.1001/jamapediatrics.2018.2740.
[20]
Lloyd J, Wilson ML, Tenovuo O, et al. Outcomes from mild and moderate traumatic brain injuries among children and adolescents: a systematic review of studies from 2008-2013[J]. Brain Inj, 2015, 29(5): 539-549. DOI: 10.3109/02699052.2014.1002003.
[21]
Sariaslan A, Sharp D, D'Onofrio B, et al. Long-term outcomes associated with traumatic brain injury in childhood and adolescence: a nationwide Swedish cohort study of a wide range of medical and social outcomes[J]. PLoS Med, 2016, 13(8): e1002103. DOI: 10.1371/journal.pmed.1002103.
[22]
De Netto RK, McKinlay A. Impact of childhood traumatic brain injury on educational outcomes and adult standard of living[J]. Disabil Rehabil, 2020, 42(17): 2444-2450. DOI: 10.1080/09638288.2019.1637948.
[23]
Chitsabesan P, Lennox C, Williams H, et al. Traumatic brain injury in juvenile offenders: findings from the comprehensive health assessment tool study and the development of a specialist linkworker service[J]. J Head Trauma Rehabil, 2015, 30(2): 106-115. DOI: 10.1097/htr.0000000000000129.
[24]
Ray B, Richardson NJ. Traumatic brain injury and recidivism among returning inmates[J]. Criminal Justice and Behavior, 2017, 44(3): 472-486.
[25]
Mollayeva T, Mollayeva S, Colantonio A. Traumatic brain injury: sex, gender and intersecting vulnerabilities[J]. Nat Rev Neurol, 2018, 14(12): 711-722. DOI: 10.1038/s41582-018-0091-y.
[26]
Theadom A, McDonald S, Starkey N, et al. Social cognition four years after mild-TBI: an age-matched prospective longitudinal cohort study[J]. Neuropsychology, 2019, 33(4): 560-567. DOI: 10.1037/neu0000516.
[27]
Thompson HJ, Rivara FP, Wang J. Effect of age on longitudinal changes in symptoms, function, and outcome in the first year after mild-moderate traumatic brain injury[J]. J Neurosci Nurs, 2020, 52(2): 46-52. DOI: 10.1097/jnn.0000000000000498.
[28]
Zhang Y, Ma Y, Chen S, et al. Long-term cognitive performance of retired athletes with sport-related concussion: a systematic review and meta-analysis[J]. Brain Sci, 2019, 9(8): 199. DOI: 10.3390/brainsci9080199.
[29]
Dikmen S, Machamer J, Temkin N. Mild traumatic brain injury: longitudinal study of cognition, functional status, and post-traumatic symptoms[J]. J Neurotrauma, 2017, 34(8): 1524-1530. DOI: 10.1089/neu.2016.4618.
[30]
McAllister TW. Mild traumatic brain injury[J]. Focus (Am Psychiatr Publ), 2016, 14(4): 410-421. DOI: 10.1176/appi.focus.20160025.
[31]
Dams-O'Connor K, Gibbons LE, Bowen JD, et al. Risk for late-life re-injury, dementia and death among individuals with traumatic brain injury: a population-based study[J]. J Neurol Neurosurg Psychiatry, 2013, 84(2): 177-182. DOI: 10.1136/jnnp-2012-303938.
[32]
Numminen HJ. The incidence of traumatic brain injury in an adult population--how to classify mild cases?[J]. Eur J Neurol, 2011, 18(3): 460-464. DOI: 10.1111/j.1468-1331.2010.03179.x.
[33]
Capizzi A, Woo J, Verduzco-Gutierrez M. Traumatic brain injury: an overview of epidemiology, pathophysiology, and medical management[J]. Med Clin North Am, 2020, 104(2): 213-238. DOI: 10.1016/j.mcna.2019.11.001.
[34]
Kannus P, Niemi S, Parkkari J, et al. Fall-induced hospital-treated traumatic brain injuries among elderly Finns in 1970-2017[J]. Arch Gerontol Geriatr, 2020, 86: 103958. DOI: 10.1016/j.archger.2019.103958.
[35]
Cogan A, McCaughey V, Scholten J. Gender differences in outcomes after traumatic brain injury among service members and veterans[J]. PM R, 2020, 12(3): 301-314. DOI: 10.1002/pmrj.12237.
[36]
MacDonald C, Johnson A, Wierzechowski L, et al. Outcome trends after US military concussive traumatic brain injury[J]. J Neurotrauma, 2017, 34(14): 2206-2219. DOI: 10.1089/neu.2016.4434.
[37]
MacDonald C, Barber J, Jordan M, et al. Early clinical predictors of 5-year outcome after concussive blast traumatic brain injury[J]. JAMA Neurol, 2017, 74(7): 821-829. DOI: 10.1001/jamaneurol.2017.0143.
[38]
Temkin N, Corrigan J, Dikmen S, et al. Social functioning after traumatic brain injury[J]. J Head Trauma Rehabil, 2009, 24(6): 460-467. DOI: 10.1097/HTR.0b013e3181c13413.
[39]
Fann JR, Ribe AR, Pedersen HS, et al. Long-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study[J]. Lancet Psychiatry, 2018, 5(5): 424-431. DOI: 10.1016/s2215-0366(18)30065-8.
[40]
Pugh MJ, Swan AA, Carlson KF, et al. Traumatic brain injury severity, comorbidity, social support, family functioning, and community reintegration among veterans of the Afghanistan and Iraq wars[J]. Arch Phys Med Rehabil, 2018, 99(2S): S40-S49. DOI: 10.1016/j.apmr.2017.05.021.
[41]
LoBue C, Cullum CM. POINT/COUNTER-POINT-beyond the headlines: the actual evidence that traumatic brain injury is a risk factor for later-in-life dementia[J]. Arch Clin Neuropsychol, 2020, 35(2): 123-127. DOI: 10.1093/arclin/acz074.
[42]
Barnes DE, Kaup A, Kirby KA, et al. Traumatic brain injury and risk of dementia in older veterans[J]. Neurology, 2014, 83(4): 312-319. DOI: 10.1212/wnl.0000000000000616.
[43]
Lee YK, Hou SW, Lee CC, et al. Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study[J]. PLoS One, 2013, 8(5): e62422. DOI: 10.1371/journal.pone.0062422.
[44]
程晓涛,金保哲,惠磊,等.轻中度颅脑损伤患者认知功能障碍特征及危险因素[J].中华脑科疾病与康复杂志(电子版), 2016, 6(1): 25-28. DOI: 10.3877/cma.j.issn.2095-123X.2016.01.006.
[45]
Yaffe K, Lwi SJ, Hoang TD, et al. Military-related risk factors in female veterans and risk of dementia[J]. Neurology, 2019, 92(3): e205-e211. DOI: 10.1212/wnl.0000000000006778.
[46]
Crane PK, Gibbons LE, Dams-O'Connor K, et al. Association of traumatic brain injury with late-life neurodegenerative conditions and neuropathologic findings[J]. JAMA Neurol, 2016, 73(9): 1062-1069. DOI: 10.1001/jamaneurol.2016.1948.
[47]
Juengst SB, Kumar RG, Wagner AK. A narrative literature review of depression following traumatic brain injury: prevalence, impact, and management challenges[J]. Psychol Res Behav Manag, 2017, 10: 175-186. DOI: 10.2147/prbm.S113264.
[48]
吕群玉,陈明明,刘刚,等.颅脑创伤后抑郁症发生机制的研究进展[J].精神医学杂志, 2020, 33(2): 143-146. DOI: 10.3969/j.issn.2095-9346.2020.02.017.
[49]
Schwarzbold M, Diaz A, Martins ET, et al. Psychiatric disorders and traumatic brain injury[J]. Neuropsychiatr Dis Treat, 2008, 4(4): 797-816. DOI: 10.2147/ndt.s2653.
[50]
Koponen S, Taiminen T, Portin R, et al. Axis I and II psychiatric disorders after traumatic brain injury: a 30-year follow-up study[J]. Am J Psychiatry, 2002, 159(8): 1315-1321. DOI: 10.1176/appi.ajp.159.8.1315.
[51]
Silver JM, Kramer R, Greenwald S, et al. The association between head injuries and psychiatric disorders: findings from the New Haven NIMH epidemiologic catchment area study[J]. Brain Inj, 2001, 15(11): 935-945. DOI: 10.1080/02699050110065295.
[52]
Yue J, Cnossen M, Winkler E, et al. Pre-injury comorbidities are associated with functional impairment and post-concussive symptoms at 3- and 6-months after mild traumatic brain injury: a TRACK-TBI study[J]. Front Neurol, 2019, 10: 343. DOI: 10.3389/fneur.2019.00343.
[53]
Weil ZM, Karelina K. Lifelong consequences of brain injuries during development: from risk to resilience[J]. Front Neuroendocrinol, 2019, 55: 100793. DOI: 10.1016/j.yfrne.2019.100793.
[54]
Bryant R, O'Donnell M, Creamer M, et al. The psychiatric sequelae of traumatic injury[J]. Am J Psychiatry, 2010, 167(3): 312-320. DOI: 10.1176/appi.ajp.2009.09050617.
[55]
Carlson K, Kehle S, Meis L, et al. Prevalence, assessment, and treatment of mild traumatic brain injury and posttraumatic stress disorder: a systematic review of the evidence[J]. J Head Trauma Rehabil, 2011, 26(2): 103-115. DOI: 10.1097/HTR.0b013e3181e50ef1.
[56]
Amen D, Raji C, Willeumier K, et al. Functional neuroimaging distinguishes posttraumatic stress disorder from traumatic brain injury in focused and large community datasets[J]. PLoS One, 2015, 10(7): e0129659. DOI: 10.1371/journal.pone.0129659.
[1] 李朝阳, 任文琦, 侯令密, 蒋燕清, 刘沁豪, 赵永真, 张梅, 钱双强, 李金穗. T1-2N1miM0期乳腺癌患者乳房切除术后前哨淋巴结微转移的处理[J]. 中华乳腺病杂志(电子版), 2024, 18(02): 85-92.
[2] 蔡大明, 陆晓峰, 王行舟, 王萌, 刘颂, 夏雪峰, 沈晓菲, 杜峻峰, 管文贤. 三级淋巴结构在胃神经内分泌瘤中的预后价值及预后预测模型构建[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 401-405.
[3] 达热拜·热达提, 刘林, 赵为民, 孟涛, 雷程, 金博, 毕建军, 李新宇, 王海江. 中低位直肠癌新辅助放化疗后侧方淋巴结清扫术的临床观察[J]. 中华普外科手术学杂志(电子版), 2024, 18(04): 415-418.
[4] 李娇娇, 张军, 徐顺. 全程新辅助治疗联合全直肠系膜切除术对局部进展期直肠癌预后的影响研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(03): 283-286.
[5] 王东阳, 林琳, 娄熙彬. SII对局部进展期胃癌nCRT+腹腔镜胃癌根治术后并发症及预后的影响研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(03): 315-318.
[6] 聂彬, 赵铁军, 于云宝, 李欢, 谢林峻. 单孔加一孔腹腔镜手术与传统腹腔镜手术治疗乙状结肠癌的疗效与分析[J]. 中华普外科手术学杂志(电子版), 2024, 18(03): 330-333.
[7] 颜晓敏, 崔嵘嵘. 23例乳腺佩吉特病的经验交流[J]. 中华普外科手术学杂志(电子版), 2024, 18(03): 353-354.
[8] 刘政宏, 王凤力, 吉亚君, 高佳. 胃癌中ELK3蛋白的表达与临床病理特征和预后的关系研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(02): 155-159.
[9] 张琳, 李婷. CRIP1在胃癌中的表达及与临床病理指标和预后的关系研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(02): 171-175.
[10] 周慧宇, 吕定阳, 双卫兵. 联合系统性免疫炎症指数和预后营养指数预测腹腔镜肾切除术后肾癌患者的预后[J]. 中华腔镜泌尿外科杂志(电子版), 2024, 18(03): 225-231.
[11] 曾谣, 谢琴, 陈显育, 王平根, 毛玲秋, 何丹玲, 杜飞, 郑希彦, 何函樨. CDC42EP2基因与肝癌预后、免疫细胞浸润关系及其对细胞迁移侵袭的影响[J]. 中华肝脏外科手术学电子杂志, 2024, 13(03): 363-369.
[12] 王文鹏, 邓露, 施丹, 胡均, 王捷夫, 云铎, 孔大陆. 脂肪酸分解代谢相关基因ABHD1和PLA2G15在结直肠癌不良预后及肿瘤进展中的研究[J]. 中华结直肠疾病电子杂志, 2024, 13(02): 101-111.
[13] 郭丹. 肩周肌群的抗阻力量训练对肩袖损伤患者术后功能恢复及预后质量的影响[J]. 中华肩肘外科电子杂志, 2024, 12(02): 115-120.
[14] 安亚楠, 王端然, 郭甜甜, 武希润. 幽门螺杆菌阴性胃黏膜相关淋巴组织淋巴瘤的研究进展[J]. 中华消化病与影像杂志(电子版), 2024, 14(03): 268-274.
[15] 陈憩, 顾于蓓. 不同亚型上消化道克罗恩病的临床特点和预后差异研究[J]. 中华消化病与影像杂志(电子版), 2024, 14(02): 121-127.
阅读次数
全文


摘要