探讨术前常规MR-T2WI直方图对脊膜瘤质地的预测价值。

回顾性分析联勤保障部队第九〇〇医院神经外科自2015年1月至2022年5月收治的40例脊膜瘤患者的临床资料。根据术中切除难易程度，将肿瘤分为软质地组和硬质地组。所有患者术前均行3.0T MRI扫描，采用ImageJ软件在T2WI矢状位上选取肿瘤最大径层面并勾画感兴趣区域（ROI），测量ROI的直方图相关参数，包括均数、中位数、众数、最大值、最小值、标准差、偏斜度和峰度，比较分析软质地组和硬质地组各项参数的差异，并将差异有统计学意义的参数绘制受试者工作特征（ROC）曲线，分析T2WI直方图对脊膜瘤质地的预测效能。

2组T2WI直方图信号值的最大值、最小值、标准差、偏斜度和峰度比较差异无统计学意义（P>0.05）。软质地组T2WI直方图信号值的均数、中位数及众数均显著大于硬质地组，差异有统计学意义（P<0.05）。瘤体软质地组的均数、中位数及众数的ROC曲线下面积分别为0.801、0.804、和0.792。均数的临界值为272.290，鉴别敏感度为91.67%，特异度为60.70%；中位数临界值为373.680，鉴别敏感度为66.70%，特异度为85.70%；众数临界值为295.350，鉴别的敏感度为83.30%，特异度为67.90%。

肿瘤瘤体T2WI直方图信号值均数、中位数、众数均可用于脊膜瘤质地的预测，其中以中位数较优。

To investigate the predictive value of preoperative conventional MR-T2WI histograms on texture of spinal meningioma.

The clinical data of 40 patients with spinal meningioma admitted to the Neurosurgery Department of 900^th Hospital of Joint Logistics Team of People's Liberation Army from January 2015 to May 2022 were analyzed retrospectively. The tumors were divided into soft and rigid groups according to the difficulty of intraoperative resection. All patients underwent 3.0T MRI scan before surgery, selected the maximum diameter level of the tumor in the T2WI sagittal position by ImageJ software and delineated the region of interest (ROI), and measured the histogram related parameters of ROI, including the mean, median, crowd, maximum, minimum, standard deviation, bias, and kurtosis. The differences between the parameters in the soft and hard texture groups were compared, and the receiver operating characteristics (ROC) curves were drawn between the statistically significant parameters, and the predictive efficacy of T2WI histogram on spinal meningioma texture was analyzed.

The maximum, minimum, standard deviation, bias, and kurtosis value of T2WI histograms in 2 groups were not significantly different (P>0.05). The mean, median, and medium values of the T2WI histogram signals in the soft texture group were significantly larger than those in the hard texture group, and the difference was statistically significant (P<0.05). The area under the ROC curve for the mean, median, and crowd of the tumor soft texture group was 0.801, 0.804, and 0.792, respectively. The cut-off value of the mean was 272.290, the discrimination sensitivity was 91.67% and the specificity was 60.70%. The median cut-off value was 373.680, the discrimination sensitivity was 66.70% and the specificity was 85.70%. The crowd cut-off value was 295.350, the discrimination sensitivity was 83.30% and the specificity was 67.90%.

The mean, median, and medium number of the T2WI histogram signals can be used to predict the texture of the spinal meningioma of the tumor, among which the median is better.