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中华神经创伤外科电子杂志 ›› 2019, Vol. 05 ›› Issue (02) : 110 -113. doi: 10.3877/cma.j.issn.2095-9141.2019.02.011

所属专题: 文献

短篇论著

后颅窝非囊结节型血管母细胞瘤术前栓塞的效果分析
朱国华1, 秦虎1, 麦麦提力·米吉提1, 李彦东1, 更·党木仁加甫1,()   
  1. 1. 830054 乌鲁木齐,新疆医科大学第一附属医院神经外科
  • 收稿日期:2019-01-04 出版日期:2019-04-15
  • 通信作者: 更·党木仁加甫
  • 基金资助:
    新疆维吾尔自治区自然科学基金(2018D01A53)

Clinical effect of preoperative embolization of non-capsular nodular hemangioblastoma in the posterior fossa

Guohua Zhu1, Hu Qin1, Mijiti Maimaitili·1, Yandong Li1, Dangmurenjiafu Geng·1,()   

  1. 1. Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:2019-01-04 Published:2019-04-15
  • Corresponding author: Dangmurenjiafu Geng·
  • About author:
    Corresponding author: Geng·Dangmurenjiafu, Email:
引用本文:

朱国华, 秦虎, 麦麦提力·米吉提, 李彦东, 更·党木仁加甫. 后颅窝非囊结节型血管母细胞瘤术前栓塞的效果分析[J]. 中华神经创伤外科电子杂志, 2019, 05(02): 110-113.

Guohua Zhu, Hu Qin, Mijiti Maimaitili·, Yandong Li, Dangmurenjiafu Geng·. Clinical effect of preoperative embolization of non-capsular nodular hemangioblastoma in the posterior fossa[J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2019, 05(02): 110-113.

目的

探讨后颅窝非囊结节型血管母细胞瘤(HB)术前栓塞的安全性和有效性。

方法

回顾性分析新疆医科大学第一附属医院神经外科中心肿瘤病区自2014年1月至2018年6月收治的12例后颅窝非囊结节型HB患者的临床资料,患者均行术前栓塞,栓塞后行显微神经外科手术切除肿瘤,观察栓塞后及术后并发症发生情况并采用KPS评分评价治疗效果。

结果

后颅窝非囊结节型HB多支血管共同参与供血,本组患者完全栓塞5例,大部分栓塞5例,部分栓塞2例。栓塞后显微神经外科手术全切11例,肿瘤次全切1例。平均手术时间5.3 h,术中出血200~1500 mL,平均出血680 mL。1例患者术后后组颅神经麻痹,发生吸入性肺炎;1例出现颅内感染。术后KPS评分均≥90分,可进行正常活动。

结论

术前栓塞是后颅窝非囊结节型HB安全有效的辅助治疗方法,可有效减少术中出血,缩短手术时间,减少手术并发症,提高患者术后生活质量。

Objective

To investigate the safety and efficacy of preoperative embolization for non-capsular nodular hemangioblastoma (HB) in the posterior fossa.

Methods

Retrospective analysis of 12 cases of posterior cranial fossa non-cystic nodular HB patients admitted to the Department of Neurosurgery, the First Affiliated Hospital of Xinjiang Medical University from January 2014 to June 2018. All patients underwent preoperative embolization and microsurgical resection after embolization. The occurrence of complications after embolization and post-operative complications were observed and the therapeutic effect was evaluated by KPS score.

Results

The posterior cranial fossa non-cystic nodular HB multi-vessels were involved in blood supply. The patients in this group were completely embolized in 5 cases, most of them were embolized in 5 cases, and some embolization in 2 cases. After embolization, 11 cases underwent microsurgery and 1 case underwent total tumor resection. The average operation time was 5.3 h; the intraoperative blood loss was 200-1500 mL, and the average bleeding was 680 mL. One patient had postoperative cranial nerve palsy and aspiration pneumonia; one patient developed intracranial infection. Postoperative KPS scores were ≥90 points, the patient can perform normal activities.

Conclusion

Preoperative embolization is a safe and effective adjuvant treatment for non-capsular nodular HB in the posterior fossa. It can effectively reduce intraoperative bleeding, shorten the operation time, reduce the complications of surgery and improve the postoperative quality of life.

图1 左侧桥小脑角区实质性血管母细胞瘤患者术前及栓塞前后的影像资料
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