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中华神经创伤外科电子杂志 ›› 2020, Vol. 06 ›› Issue (03) : 183 -186. doi: 10.3877/cma.j.issn.2095-9141.2020.03.012

所属专题: 文献

综述

胰岛素样生长因子-1在垂体瘤诊断及治疗中的应用
徐兆威1, 柏瑞1, 段虎斌1, 范益民1,()   
  1. 1. 030000 太原,山西医科大学第一医院神经外科
  • 收稿日期:2019-10-17 出版日期:2020-06-15
  • 通信作者: 范益民
  • 基金资助:
    国家自然科学基金青年科学基金(30600637)

Application of IGF-1 in the diagnosis and treatment of pituitary tumor

Zhaowei Xu1, Rui Bai1, Hubin Duan1, Yimin Fan1,()   

  1. 1. Department of Neurosurgery, The First Hospital of Shanxi Medical University, Taiyuan 030000, China
  • Received:2019-10-17 Published:2020-06-15
  • Corresponding author: Yimin Fan
  • About author:
    Corresponding author: Fan Yimin, Email:
引用本文:

徐兆威, 柏瑞, 段虎斌, 范益民. 胰岛素样生长因子-1在垂体瘤诊断及治疗中的应用[J/OL]. 中华神经创伤外科电子杂志, 2020, 06(03): 183-186.

Zhaowei Xu, Rui Bai, Hubin Duan, Yimin Fan. Application of IGF-1 in the diagnosis and treatment of pituitary tumor[J/OL]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2020, 06(03): 183-186.

胰岛素样生长因子-1(IGF-1)及其受体是胰岛素样生长因子系统的组成部分,在神经系统、呼吸系统及消化系统等肿瘤的发生演变过程中发挥重要作用,通过对IGF-1及其受体与肿瘤的演变关系进行干预,为肿瘤的临床诊断及治疗提供帮助。垂体瘤是颅内较常见的肿瘤,IGF-1可在垂体瘤中表达。本文从IGF-1与肿瘤的发生发展机制,及其在垂体瘤的表达与应用作一综述。

Insulin-like growth factor-1 (IGF-1) and its receptor are components of the insulin-like growth factor system and play an important role in the development and evolution of tumors such as nervous system, respiratory system and digestive system. Through the intervention of the relationship between IGF-1 and its receptor and tumor evolution, it can provide help for the clinical diagnosis and treatment of tumors. Pituitary tumors are relatively common intracranial tumors. Studies have found that IGF-1 is expressed in pituitary tumors. This article describes the expression and application of IGF-1 and tumors in pituitary tumor.

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