[30] |
Avery MA, Rooney TM, Pandya JD, et al.WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering[J]. Curr Biol, 2012,22(7):596-600.
|
[31] |
Kitay BM, McCormack R, Wang Y, et al. Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria[J]. Hum Mol Genet, 2013, 22(8):1601-1614.
|
[32] |
Wishart TM, Pemberton HN, James SR, et al. Modified cell cycle status in a mouse model of altered neuronal vulnerability(slow Wallerian degeneration; Wlds)[J]. Genome Biol, 2008,9(6):R101.
|
[33] |
Vande Velde C, Garcia ML, Yin X, et al. The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease[J].Neuromolecular Med,2004,5(3):193-203.
|
[34] |
Zhu X, Libby RT, de Vries WN, et al. Mutations in a P-type ATPase gene cause axonal degeneration[J]. PLoS Genet, 2012,8(8):e1002853.
|
[35] |
Adams JH,Doyle D,Ford I,et al.Diffuse axonal injury in head injury: definition, diagnosis and grading[J]. Histopathology,1989,15(1):49-59.
|
[36] |
Graham DI, Smith C, Reichard R, et al. Trials and tribulations of using beta-amyloid precursor protein immunohistochemistry to evaluate traumatic brain injury in adults[J]. Forensic Sci Int,2004,146:89-96.
|
[37] |
Mac Donald CL, Dikranian K, Song SK, et al. Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injury[J]. Exp Neurol, 2007,205(1):116-131.
|
[38] |
Qin YY, Li MW, Zhang S, et al. In vivo quantitative wholebrain diffusion tensor imaging analysis of APP/PS1 transgenic mice using voxel- based and atlas- based methods[J].Neuroradiology,2013,55(8):1027-1038.
|
[39] |
Greer JE, Povlishock JT, Jacobs KM. Electrophysiological abnormalities in both axotomized and nonaxotomized pyramidal neurons following mild traumatic brain injury[J]. J Neurosci,2012,32(19):6682-6687.
|
[1] |
Weishaupt N, Silasi G, Colbourne F, et al. Secondary damage in the spinal cord after motor cortex injury in rats[J]. J Neurotrauma,2010,27(8):1387-1397.
|
[2] |
Burke RE. Intracellular signalling pathways in dopamine cell death and axonal degeneration[J]. Prog Brain Res, 2010, 183:79-97.
|
[3] |
King AE, Dickson TC, Blizzard CA, et al. Neuron- glia interactions underlie ALS-like axonal cytoskeletal pathology[J].Neurobiol Aging 2011,32(3):459-469.
|
[4] |
Hubert T, Wu Z, Chisholm AD, et al. S6 kinase inhibits intrinsic axon regeneration capacity via AMP kinase in Caenorhabditis elegans[J].J Neurosci,2014,34(3):758-763.
|
[5] |
Willyard C. Stem cells: A time to heal[J]. Nature, 2013,503(7475):S4-S6.
|
[6] |
Sahakyants T, Lee JY, Friedrich PF, et al. Return of motor function after repair of a 3-cm gap in a rabbit peroneal nerve:a comparison of autograft, collagen conduit, and conduit filled with collagen-GAG matrix[J]. J Bone Joint Surg Am, 2013,95(21):1952-1958.
|
[7] |
Kerschensteiner M, Schwab ME, Lichtman JW, et al. In vivo imaging of axonal degeneration and regeneration in the injured spinal cord[J].Nat Med,2005,11(5):572-577.
|
[8] |
Knoferle J, Koch JC, Ostendorf T, et al. Mechanisms of acute axonal degeneration in the optic nerve in vivo[J]. Proc Natl Acad Sci U S A,2010,107(13):6064-6069.
|
[9] |
Vosler PS, Brennan CS, Chen J. Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration[J]. Mol Neurobiol,2008,38(1):78-100.
|
[10] |
Koch JC, Knoferle J, Tonges L, et al. Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium- dependent manner[J]. Autophagy, 2010, 6(5):658-659.
|
[11] |
Sievers C, Platt N, Perry VH, et al. Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential[J].Neurosci Res,2003,46(2):161-169.
|
[12] |
Beirowski B, Adalbert R, Wagner D, et al. The progressive nature of Wallerian degeneration in wild- type and slow Wallerian degeneration (WldS) nerves[J]. BMC Neurosci,2005,6(2):6.
|
[13] |
Vavlitou N, Sargiannidou I, Markoullis K, et al. Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy[J].J Neuropathol Exp Neurol,2010,69(9):945-958.
|
[14] |
Luo L, O'Leary DD. Axon retraction and degeneration in development and disease[J]. Annu Rev Neurosci, 2005, 28:127-156.
|
[15] |
Nikic I, Merkler D, Sorbara C, et al.A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis[J].Nat Med,2011,17(4):495-499.
|
[16] |
Stirling DP, Stys PK. Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation[J]. Trends Mol Med,2010,16(4):160-170.
|
[17] |
Li Y, Song J, Liu X, et al. High expression of STIM1 in the early stages of diffuse axonal injury[J]. Brain Res, 2013,1495(2):95-102.
|
[18] |
Kampfl A, Posmantur R, Nixon R, et al. mu-calpain activation and calpain- mediated cytoskeletal proteolysis following traumatic brain injury[J]. J Neurochem, 1996, 67(4):1575-1583.
|
[19] |
Saatman KE, Creed J, Raghupathi R. Calpain as a therapeutic target in traumatic brain injury[J]. Neurotherapeutics, 2010,7(1):31-42.
|
[20] |
Barrientos SA,Martinez NW,Yoo S,et al.Axonal degeneration is mediated by the mitochondrial permeability transition pore[J].J Neurosci,2011,31(3):966-978.
|
[21] |
Kilinc D, Gallo G, Barbee KA. Mechanical membrane injury induces axonal beading through localized activation of calpain[J].Exp Neurol,2009,219(2):553-561.
|
[22] |
Ally S, Larson AG, Barlan K, et al. Opposite-polarity motors activate one another to trigger cargo transport in live cells[J]. J Cell Biol,2009,187(7):1071-1082.
|
[23] |
Zhao C,Takita J,Tanaka Y, et al. Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta[J].Cell,2001,105(5):587-597.
|
[24] |
Hafezparast M, Klocke R, Ruhrberg C, et al. Mutations in dynein link motor neuron degeneration to defects in retrograde transport[J].Science,2003,300(5620):808-812.
|
[25] |
Byrne AB,Walradt T,Gardner KE,et al.Insulin/IGF1 signaling inhibits age- dependent axon regeneration[J]. Neuron, 2014,81(3):561-573.
|
[26] |
Lunn ER, Perry VH, Brown MC, et al. Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve[J].Eur J Neurosci,1989,1(1):27-33.
|
[27] |
Wright AK,Wishart TM,Ingham CA,et al.Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose[J].PLoS One,2010,5(11):e15108.
|
[28] |
Conforti L, Tarlton A, Mack TG, et al. A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration(WldS)mouse[J].Proc Natl Acad Sci U S A,2000,97(21):11377-11382.
|
[29] |
Fang Y, Soares L, Teng X, et al.A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity[J].Curr Biol,2012,22(7):590-595.
|