外伤后继发ⅡA型局灶性皮质发育障碍一例

病例报告

外伤后继发ⅡA型局灶性皮质发育障碍一例

刘仕勇¹, 杨辉¹^,^†(

)

Shiyong Liu, Hui Yang^†()

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图1 外伤后继发ⅡA型局灶性皮质发育障碍患者的影像学资料注：A图示患者11个月大时受伤，CT显示颅内出血；B图示受伤后3个月行MRI 检查发现左额顶硬膜下占位；C 图示术前CT 显示左额大片钙化；D 图示术前MRI 显示左额FCD，局部脑回紊乱，灰质增厚，脑沟加深(箭头所示)

Fig.1 Imaging data of the patient

图2 外伤后继发ⅡA型局灶性皮质发育患者左额局部皮质的病理学资料(HE染色×400) 注：A 图显示显示皮质分层紊乱(bar=200 μm)；B 图显示神经元排列紊乱，轴突走向异常(bar=50 μm)；C 图显示可见到较大的异形神经元(bar=50μm)

Fig.2 Pathological data of the patient's left frontal cortex(HE staining)

[1]	Blumcke I, Thom M, Aronica E, et al. The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission[J].Epilepsia,2011,52(1):158-174.
[2]	Krsek P, Jahodova A, Maton B, et al. Low-grade focal cortical dysplasia is associated with prenatal and perinatal brain injury[J].Epilepsia,2010,51(12):2440-2448.
[3]	Lombroso CT. Can early postnatal closed head injury induce cortical dysplasia[J].Epilepsia,2000,41(2):245-253.
[4]	Kremer S, De Saint Martin A, Minotti L, et al. Focal cortical dysplasia possibly related to a probable prenatal ischemic injury[J]. J Neuroradiol,2002,29(3):200-203.

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